CAS 62732-44-9|Ipidacrine

Introduction：Basic information about CAS 62732-44-9|Ipidacrine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Ipidacrine BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Synonyms

Common Name	Ipidacrine
CAS Number	62732-44-9	Molecular Weight	188.26900
Density	1.17 g/cm3	Boiling Point	367.969ºC at 760 mmHg
Molecular Formula	C₁₂H₁₆N₂	Melting Point	/
MSDS	/	Flash Point	203.991ºC

Names

Name	2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine
Synonym	More Synonyms

Ipidacrine BiologicalActivity

Description	2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-amine is a pharmaceutically active compound which is a nootropic agent that acts as cholinesterase inhibitor and is used in treatment of Alzheimer disease[1].
Related Catalog	Research Areas >>Neurological DiseaseSignaling Pathways >>Neuronal Signaling >>AChE
References	[1]. A.Dubika, K. Veldre, et al. Phase Transitions of Ipidacrine Hydrochloride Polymorphs and Hydrates. The Open Conference Proceedings Journal, 2011, 2, 21-27.

Chemical & Physical Properties

Density	1.17 g/cm3
Boiling Point	367.969ºC at 760 mmHg
Molecular Formula	C₁₂H₁₆N₂
Molecular Weight	188.26900
Flash Point	203.991ºC
Exact Mass	188.13100
PSA	38.91000
LogP	2.61250
Index of Refraction	1.634
InChIKey	YLUSMKAJIQOXPV-UHFFFAOYSA-N
SMILES	Nc1c2c(nc3c1CCC3)CCCC2

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GY5897400

CHEMICAL NAME :: 1H-Cyclopenta(b)quinolin-9-amine, 2,3,5,6,7,8-hexahydro-

CAS REGISTRY NUMBER :: 62732-44-9

BEILSTEIN REFERENCE NO. :: 0475930

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H16-N2

MOLECULAR WEIGHT :: 188.30

WISWESSER LINE NOTATION :: TC566 BNT&TJ HZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 39 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - miosis (pupillary constriction) Behavioral - tremor Gastrointestinal - hypermotility, diarrhea

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 11,184,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 52 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 23,709,1989

Safety Information

Hazard Codes	Xi

Synonyms

Amiridine

Ipidacrine

9-amino-2,3,5,6,7,8-hexahydro-1-cyclopenta<b>quinoline

Amiridin

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