Introduction：Basic information about CAS 72063-39-9|Spinosin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Spinosin |
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| CAS Number | 72063-39-9 | Molecular Weight | 608.545 |
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| Density | 1.7±0.1 g/cm3 | Boiling Point | 901.4±65.0 °C at 760 mmHg |
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| Molecular Formula | C28H32O15 | Melting Point | 258 °C |
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| MSDS | / | Flash Point | 296.7±27.8 °C |
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Names
| Name | spinosin |
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| Synonym | More Synonyms |
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Spinosin BiologicalActivity
| Description | Spinosyn a C-glycoside flavonoid isolated from the seeds of Zizyphus jujube, with neuroprotective effects. Spinosin inhibits Aβ1-42 production and aggregation via activating Nrf2/HO-1 pathway[1][2][3]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
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| References | [1]. Jung IH, et al. Ameliorating effect of spinosin, a C-glycoside flavonoid, on scopolamine-induced memory impairment in mice. Pharmacol Biochem Behav. 2014 May;120:88-94. [2]. Xu F, et al. Neuroprotective Effects of Spinosin on Recovery of Learning and Memory in a Mouse Model of Alzheimer's Disease. Biomol Ther (Seoul). 2019 Jan 1;27(1):71-77. [3]. Zhang X, et al. Spinosin Inhibits Aβ1-42 Production and Aggregation via Activating Nrf2/HO-1 Pathway. Biomol Ther (Seoul). 2019 Dec 3. |
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Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
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| Boiling Point | 901.4±65.0 °C at 760 mmHg |
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| Melting Point | 258 °C |
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| Molecular Formula | C28H32O15 |
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| Molecular Weight | 608.545 |
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| Flash Point | 296.7±27.8 °C |
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| Exact Mass | 608.174133 |
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| PSA | 249.20000 |
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| LogP | -1.04 |
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| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
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| Index of Refraction | 1.734 |
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| InChIKey | VGGSULWDCMWZPO-ODEMIOGVSA-N |
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| SMILES | COc1cc2oc(-c3ccc(O)cc3)cc(=O)c2c(O)c1C1OC(CO)C(O)C(O)C1OC1OC(CO)C(O)C(O)C1O |
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Safety Information
Synonyms
| 6-(2-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one |
| Spinosin |
| X1238 |
| 6-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxychromen-4-one |
| D-Glucitol, 1,5-anhydro-2-O-β-D-glucopyranosyl-1-C-[5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4-oxo-4H-1-benzopyran-6-yl]-, (1S)- |
| 4H-1-Benzopyran-4-one, 6-(2-O-β-D-glucopyranosyl-β-D-glucopyranosyl)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy- |
| (1S)-1,5-Anhydro-2-O-β-D-glucopyranosyl-1-[5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4-oxo-4H-chromen-6-yl]-D-glucitol |
