Introduction:Basic information about CAS 72580-54-2|(R)-pyrrolidine-3-carboxylic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (R)-pyrrolidine-3-carboxylic acid |
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| CAS Number | 72580-54-2 | Molecular Weight | 115.131 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 252.2±33.0 °C at 760 mmHg |
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| Molecular Formula | C5H9NO2 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | 106.3±25.4 °C |
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Names
| Name | (R)-(-)-Pyrrolidine-3-carboxylic Acid |
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| Synonym | More Synonyms |
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(R)-pyrrolidine-3-carboxylic acid BiologicalActivity
| Description | (R)-Pyrrolidine-3-carboxylic acid is a proline derivative[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| In Vitro | Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1]. |
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| References | [1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 252.2±33.0 °C at 760 mmHg |
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| Molecular Formula | C5H9NO2 |
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| Molecular Weight | 115.131 |
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| Flash Point | 106.3±25.4 °C |
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| Exact Mass | 115.063332 |
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| PSA | 49.33000 |
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| LogP | -0.47 |
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| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
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| Index of Refraction | 1.487 |
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| InChIKey | JAEIBKXSIXOLOL-SCSAIBSYSA-N |
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| SMILES | O=C(O)C1CCNC1 |
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| Storage condition | 2-8°C |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi |
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| RIDADR | NONH for all modes of transport |
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| HS Code | 2942000000 |
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Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Articles13
More Articles
| Diastereocontrolled synthesis of enantioenriched 3,4-disubstituted beta-prolines. J. Org. Chem. 72 , 398, (2007) Enantioenriched 3,4-disubstituted beta-prolines have been prepared with a high diastereocontrol through a carbometalation reaction or through a domino Michael addition/carbometalation reaction. | |
| Beta-proline analogues as agonists at the strychnine-sensitive glycine receptor. J. Med. Chem. 35 , 233, (1992) 3-Carboxy-3,4-dehydropyrrolidine was found to bind with affinity equal to that of glycine in a [3H]strychnine binding assay. Simple substitution of the 1-, 2-, 4-, or 5-position resulted in marked los... | |
| Endomorphin-1 analogues containing beta-proline are mu-opioid receptor agonists and display enhanced enzymatic hydrolysis resistance. J. Med. Chem. 45(12) , 2571-8, (2002) In this paper we describe the synthesis and affinity toward the mu-opioid receptor of some tetrapeptides obtained from endomorphin-1, H-Tyr-Pro-Trp-Phe-NH(2) (1), by substituting each amino acid in tu... | |
Synonyms
| 3-Pyrrolidinecarboxylic acid |
| (S)-Pyrrolidine-3-carboxylic acid |
| Pyrrolidine-3-carboxylic acid |
| UNII:XQ9918NB1D |
| MFCD06738463 |
| (R)-pyrrolidine-3-carboxylic acid |