CAS 10284-63-6|D-Pinitol
| Common Name | D-Pinitol | ||
|---|---|---|---|
| CAS Number | 10284-63-6 | Molecular Weight | 194.182 |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 317.2±42.0 °C at 760 mmHg |
| Molecular Formula | C7H14O6 | Melting Point | 178-185ºC |
| MSDS | ChineseUSA | Flash Point | 145.6±27.9 °C |
Names
| Name | D-pinitol |
|---|---|
| Synonym | More Synonyms |
D-Pinitol BiologicalActivity
| Description | D-pinitol (3-O-Methyl-D-chiro-inositol) is a natural compound presented in several plants, like Pinaceae and Leguminosae plants. D-pinitol exerts hypoglycemic activity and protective effects in the cardiovascular system[1][2]. |
|---|---|
| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>Others |
| In Vitro | D-pinitol promotes apoptosis in MCF-7 cells via induction of p53 and Bax and inhibition of Bcl-2 and NF-κB[3]. |
| References | [1]. Gao Y, et al. Effects of D-Pinitol on Insulin Resistance through the PI3K/Akt Signaling Pathway in Type 2Diabetes Mellitus Rats. J Agric Food Chem. 2015 Jul 8;63(26):6019-26. [2]. Moreira LN, et al. Activation of eNOS by D-pinitol Induces an Endothelium-Dependent Vasodilatation in MouseMesenteric Artery. Front Pharmacol. 2018 May 22;9:528. [3]. Rengarajan T, et al. D-pinitol promotes apoptosis in MCF-7 cells via induction of p53 and Bax and inhibition of Bcl-2 and NF-κB. Asian Pac J Cancer Prev. 2014;15(4):1757-62. |
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 317.2±42.0 °C at 760 mmHg |
| Melting Point | 178-185ºC |
| Molecular Formula | C7H14O6 |
| Molecular Weight | 194.182 |
| Flash Point | 145.6±27.9 °C |
| Exact Mass | 194.079041 |
| PSA | 110.38000 |
| LogP | -0.74 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.588 |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | C;F |
| Risk Phrases | R11 |
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2909499000 |
Customs
| HS Code | 2909499000 |
|---|---|
| Summary | 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |
Articles29
More Articles| Attenuation of oxidative stress and alteration of hepatic tissue ultrastructure by D-pinitol in streptozotocin-induced diabetic rats. Free Radic. Res. 44(6) , 668-78, (2010) The present study was aimed to investigate the effect of D-pinitol on hyperglycaemia mediated oxidative stress by analysing the hepatic antioxidant competence, pro-inflammatory cytokines and ultrastru... | |
| The immunosuppressive effects of Agyrolobium roseum and pinitol in experimental animals. Int. Immunopharmacol. 11(2) , 286-91, (2011) Argyrolobium roseum (Papilionaceae) is a sexually reproducing, rare, annual herb that grows in tropical and sub-temperate tracts of the north-western Himalayan region of the Indian subcontinent. The p... | |
| Determination of D-pinitol in carob syrup. Int. J. Food Sci. Nutr. 62(6) , 572-6, (2011) Carob syrup is a traditional product native to the Mediterranean region, containing a high concentration of sugar, phenolic compounds and minerals. d-pinitol is a bioactive component extracted from le... |
Synonyms
| PINITOL,D |
| Matezitol |
| 1,2,3,4,5-Cyclohexanepentol, 6-methoxy-, (1β,2α,3α,4α,5β,6α)- |
| MFCD00216659 |
| D-PINTIOL |
| (1R,2S,3r,4R,5S,6r)-6-Methoxy-1,2,3,4,5-cyclohexanepentol |
| (1R,2S,3r,4R,5S,6r)-6-Methoxycyclohexane-1,2,3,4,5-pentol |
| CathartoMannitol |
| 3-O-methyl ether of D-chiro-inositol |
| 3-O-Methyl-D-chiro-inositol |
| 1D-3-O-methyl-chiro-inositol |
| Sennitol |
| O-methyl inositol |
| D-Pinitol |
| Pinit |
