Introduction：Basic information about CAS 41906-86-9|nitrocefin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | nitrocefin |
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| CAS Number | 41906-86-9 | Molecular Weight | 516.504 |
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| Density | 1.7±0.1 g/cm3 | Boiling Point | 872.0±65.0 °C at 760 mmHg |
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| Molecular Formula | C21H16N4O8S2 | Melting Point | >99℃ |
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| MSDS | / | Flash Point | 481.2±34.3 °C |
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Names
| Name | nitrocefin |
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| Synonym | More Synonyms |
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nitrocefin BiologicalActivity
| Description | Nitrocefin is a chromogenic β-lactamase substrate that undergoes distinctive color change from yellow to red as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on β-lactamase-resistant antibiotics[1]. |
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| Related Catalog | Research Areas >>Infection |
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| References | [1]. Shannon K, Phillips I. beta-Lactamase detection by three simple methods: Intralactam, nitrocefin and acidimetric. J Antimicrob Chemother. 1980 Sep;6(5):617-21. |
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Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
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| Boiling Point | 872.0±65.0 °C at 760 mmHg |
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| Melting Point | >99℃ |
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| Molecular Formula | C21H16N4O8S2 |
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| Molecular Weight | 516.504 |
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| Flash Point | 481.2±34.3 °C |
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| Exact Mass | 516.040955 |
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| PSA | 231.89000 |
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| LogP | 1.04 |
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| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
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| Index of Refraction | 1.749 |
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Synonyms
| (6R-(3(E),6a,7b))-3-(2-(2,4-Dinitrophenyl)ethenyl)-8-oxo-7-((2-thienylacetyl)amino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid |
| 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(E)-2-(2,4-dinitrophenyl)ethenyl]-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-, (6R,7R)- |
| nitrocefin |
| (6R,7R)-3-[(E)-2-(2,4-Dinitrophenyl)vinyl]-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
