Introduction：Basic information about CAS 102649-79-6|SC-10, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | SC-10 |
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| CAS Number | 102649-79-6 | Molecular Weight | 339.88 |
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| Density | 1.192g/cm3 | Boiling Point | 483.2ºC at 760 mmHg |
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| Molecular Formula | C17H22ClNO2S | Melting Point | / |
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| MSDS | / | Flash Point | 246ºC |
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Names
| Name | N-(N-Heptyl)-5-chloro-1-naphthalenesulfonamide |
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| Synonym | More Synonyms |
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SC-10 BiologicalActivity
| Description | SC-10 is a direct activator of PKC[1]. |
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| Related Catalog | Signaling Pathways >>Epigenetics >>PKCResearch Areas >>CancerSignaling Pathways >>TGF-beta/Smad >>PKC |
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| In Vitro | SC-10在白血病原始细胞上表现出适度的生物学效应，但不能增强这些细胞对细胞毒性药物的凋亡反应[1]。 SC-10抑制了Ara-C引起的凋亡反应[1]。 |
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| References | [1]. Gerold Meinhardt, et al. Effect of novel modulators of protein kinase C activity upon chemotherapy-induced differentiation and apoptosis in myeloid leukemic cells. Anticancer Drugs. 2002 Aug;13(7):725-33. |
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Chemical & Physical Properties
| Density | 1.192g/cm3 |
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| Boiling Point | 483.2ºC at 760 mmHg |
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| Molecular Formula | C17H22ClNO2S |
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| Molecular Weight | 339.88 |
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| Flash Point | 246ºC |
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| Exact Mass | 339.10600 |
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| PSA | 54.55000 |
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| LogP | 6.21360 |
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| Vapour Pressure | 1.72E-09mmHg at 25°C |
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| Index of Refraction | 1.573 |
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| InChIKey | MJMJERJFCHYXEM-UHFFFAOYSA-N |
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| SMILES | CCCCCCCNS(=O)(=O)c1cccc2c(Cl)cccc12 |
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Synonyms
