CAS 607-57-8|2-Nitro-9H-fluorene

Introduction：Basic information about CAS 607-57-8|2-Nitro-9H-fluorene, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
4. Safety Information
5. Customs
6. Articles50
7. Synonyms

Common Name	2-Nitro-9H-fluorene
CAS Number	607-57-8	Molecular Weight	211.216
Density	1.3±0.1 g/cm3	Boiling Point	374.7±21.0 °C at 760 mmHg
Molecular Formula	C₁₃H₉NO₂	Melting Point	156-158 °C(lit.)
MSDS	ChineseUSA	Flash Point	185.2±14.9 °C
Symbol	GHS08, GHS09	Signal Word	Warning

Names

Name	2-nitrofluorene
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	374.7±21.0 °C at 760 mmHg
Melting Point	156-158 °C(lit.)
Molecular Formula	C₁₃H₉NO₂
Molecular Weight	211.216
Flash Point	185.2±14.9 °C
Exact Mass	211.063324
PSA	45.82000
LogP	3.89
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.677
InChIKey	XFOHWECQTFIEIX-UHFFFAOYSA-N
SMILES	O=[N+]([O-])c1ccc2c(c1)Cc1ccccc1-2
Stability	Stable. Incompatible with strong oxidizing agents.
Water Solubility	Insoluble

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LL8225000

CHEMICAL NAME :: 9H-Fluorene, 2-nitro-

CAS REGISTRY NUMBER :: 607-57-8

BEILSTEIN REFERENCE NO. :: 1877983

LAST UPDATED :: 199710

DATA ITEMS CITED :: 44

MOLECULAR FORMULA :: C13-H9-N-O2

MOLECULAR WEIGHT :: 211.23

WISWESSER LINE NOTATION :: L B656 HHJ ENW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3400 mg/kg/23W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Skin and Appendages - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 310 mg/kg/79W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors Endocrine - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4000 mg/kg

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors

TYPE OF TEST :: Morphological transformation

TYPE OF TEST :: DNA adduct

TYPE OF TEST :: Unscheduled DNA synthesis

TYPE OF TEST :: Sister chromatid exchange

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 10 umol/L

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 4,1,1982 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 46,277,1989 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 46,277,1989 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 46,291,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7137 No. of Facilities: 75 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 149 (estimated)

Safety Information

Symbol	GHS08, GHS09
Signal Word	Warning
Hazard Statements	H351-H411
Precautionary Statements	P273-P281
Personal Protective Equipment	Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	Xn:Harmful;
Risk Phrases	R40;R68
Safety Phrases	S36/37-S61
RIDADR	UN 3077 9/PG 3
WGK Germany	3
RTECS	LL8225000
Hazard Class	9.0
HS Code	29042000

Customs

HS Code	2904209090
Summary	2904209090 derivatives containing only nitro or only nitroso groups。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles50

Genotoxicity testing of esterified propoxylated glycerol (EPG).

Regul Toxicol Pharmacol 70 Suppl 2 , S131-42, (2014)

Four versions of esterified propoxylated glycerols (EPGs) were evaluated for potential genotoxicity using a range of in vitro and in vivo assays. H-EPG-05 HR/SO 9:1, H-EPG-05 soyate, and H-EPG-14 soya...

Genotoxic properties of representatives of alkylindazoles and aminoalkyl-indoles which are consumed as synthetic cannabinoids.

Food Chem. Toxicol. 80 , 130-6, (2015)

Synthetic cannabinoids (SCs) cause similar effects as cannabis and are sold in herbal mixtures. Recent investigations indicate that some of these drugs possess genotoxic properties. Therefore, we test...

Safety evaluation of the human-identical milk monosaccharide sialic acid (N-acetyl-d-neuraminic acid) in Sprague-Dawley rats.

Regul Toxicol Pharmacol 70(2) , 482-91, (2014)

N-Acetyl-d-neuraminic acid (Neu5Ac) is the predominant form of sialic acid (Sia) in humans, while other mammals express Sia as a mixture with N-glycolyl-d-neuraminic acid (Neu5Gc). Neu5Ac occurs in hi...

Synonyms

2-Nitro-9H-fluorene

EINECS 210-138-5

MFCD00001117

9H-Fluorene, 2-nitro-

2-Nitrofluorene

L B656 HHJ ENW

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