Introduction：Basic information about CAS 480-56-8|Lecanoricacid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Lecanoricacid |
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| CAS Number | 480-56-8 | Molecular Weight | 318.278 |
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| Density | 1.5±0.1 g/cm3 | Boiling Point | 557.1±50.0 °C at 760 mmHg |
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| Molecular Formula | C16H14O7 | Melting Point | 175-176ºC |
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| MSDS | / | Flash Point | 208.3±23.6 °C |
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Names
| Name | o-orsellinate depside |
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| Synonym | More Synonyms |
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Lecanoricacid BiologicalActivity
| Description | Lecanoric acid is a histidine-decarboxylase inhibitor isolated from fungus. The inhibition by lecanoric acid is competitive with histidineand noncompetitive with pyridoxal phosphate. Lecanoric acid did not inhibit aromatic amino acid decarboxylase[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Others >>Others |
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| References | [1]. Umezawa H, et al. Isolation of lecanoric acid, an inhibitor of histidine decarboxylase from a fungus. J Antibiot (Tokyo). 1974;27(8):587-596. |
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Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
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| Boiling Point | 557.1±50.0 °C at 760 mmHg |
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| Melting Point | 175-176ºC |
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| Molecular Formula | C16H14O7 |
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| Molecular Weight | 318.278 |
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| Flash Point | 208.3±23.6 °C |
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| Exact Mass | 318.073944 |
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| PSA | 124.29000 |
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| LogP | 4.39 |
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| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
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| Index of Refraction | 1.675 |
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| InChIKey | HEMSJKZDHNSSEW-UHFFFAOYSA-N |
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| SMILES | Cc1cc(OC(=O)c2c(C)cc(O)cc2O)cc(O)c1C(=O)O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- VH3709950
- CHEMICAL NAME :
- beta-Resorcylic acid, 6-methyl-, 4-(6-methyl-beta-resorcylate)
- CAS REGISTRY NUMBER :
- 480-56-8
- BEILSTEIN REFERENCE NO. :
- 2172778
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C16-H14-O7
- MOLECULAR WEIGHT :
- 318.30
- WISWESSER LINE NOTATION :
- QVR BQ F1 DOVR DQ B1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 27,587,1974
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Safety Information
Synonyms
| Benzoic acid, 4-[(2,4-dihydroxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methyl- |
| 4-[(2,4-Dihydroxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methylbenzoic acid |
| 4-(2,4-dihydroxy-6-methylbenzoyl)oxy-2-hydroxy-6-methylbenzoic acid |
| o-orsellinate depside |
| lecanoric aicd |
| Lecanoric acid |
| lecanolic acid |
| 2,4-Dihydroxy-6-methylbenzoic acid 4-carboxy-3-hydroxy-5-methylphenyl ester |
| Lecanoricacid |
| Lecanorsaeure |
