Introduction：Basic information about CAS 104004-96-8|N-Demethyl Mifepristone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N-Demethyl Mifepristone |
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| CAS Number | 104004-96-8 | Molecular Weight | 415.56700 |
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| Density | 1.19g/cm3 | Boiling Point | 628.9ºC at 760mmHg |
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| Molecular Formula | C28H33NO2 | Melting Point | / |
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| MSDS | / | Flash Point | 334.1ºC |
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Names
| Name | N-Demethyl Mifepristone |
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| Synonym | More Synonyms |
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N-Demethyl Mifepristone BiologicalActivity
| Description | N-Demethyl Mifepristone (RU 42633) is an active metabolite of Mifepristone (HY-13683). The affinities of N-Demethyl Mifepristone to the glucocorticoid receptor is 61% compared with 100% for Mifepristone[1]. |
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| Related Catalog | Research Areas >>EndocrinologySignaling Pathways >>GPCR/G Protein >>Glucocorticoid Receptor |
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| References | [1]. Nguyen D, et al. Effects of Ketoconazole on the Pharmacokinetics of Mifepristone, a Competitive Glucocorticoid Receptor Antagonist, in Healthy Men. Adv Ther. 2017 Oct;34(10):2371-2385. |
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Chemical & Physical Properties
| Density | 1.19g/cm3 |
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| Boiling Point | 628.9ºC at 760mmHg |
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| Molecular Formula | C28H33NO2 |
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| Molecular Weight | 415.56700 |
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| Flash Point | 334.1ºC |
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| Exact Mass | 415.25100 |
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| PSA | 49.33000 |
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| LogP | 5.45520 |
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| Vapour Pressure | 1.11E-16mmHg at 25°C |
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| Index of Refraction | 1.625 |
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| InChIKey | IBLXOBHABOVXDY-WKWWZUSTSA-N |
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| SMILES | CC#CC1(O)CCC2C3CCC4=CC(=O)CCC4=C3C(c3ccc(NC)cc3)CC21C |
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Synonyms
| (8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-11-[4-(methylamino)phenyl]-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one |
