CAS 17834-03-6|7-hydroxy Warfarin
| Common Name | 7-hydroxy Warfarin | ||
|---|---|---|---|
| CAS Number | 17834-03-6 | Molecular Weight | 324.33 |
| Density | 1.384g/cm3 | Boiling Point | 540.2ºC at 760mmHg |
| Molecular Formula | C19H16O5 | Melting Point | 220ºC |
| MSDS | ChineseUSA | Flash Point | 197.7ºC |
| Symbol | GHS05, GHS07 | Signal Word | Danger |
Names
| Name | 7-Hydroxy Warfarin |
|---|---|
| Synonym | More Synonyms |
7-hydroxy Warfarin BiologicalActivity
| Description | 7-Hydroxywarfarin is a Warfarin analog with anticoagulant activity[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. Obaseki AO, Coker HB. The anticoagulant activity of some selected warfarin analogues. J Pharm Pharmacol. 1987 Feb;39(2):142-4. |
Chemical & Physical Properties
| Density | 1.384g/cm3 |
|---|---|
| Boiling Point | 540.2ºC at 760mmHg |
| Melting Point | 220ºC |
| Molecular Formula | C19H16O5 |
| Molecular Weight | 324.33 |
| Flash Point | 197.7ºC |
| Exact Mass | 324.10000 |
| PSA | 87.74000 |
| LogP | 3.31520 |
| Vapour Pressure | 1.68E-12mmHg at 25°C |
| Index of Refraction | 1.658 |
| InChIKey | SKFYEJMLNMTTJA-UHFFFAOYSA-N |
| SMILES | CC(=O)CC(c1ccccc1)c1c(O)c2ccc(O)cc2oc1=O |
Safety Information
| Symbol | GHS05, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H318 |
| Precautionary Statements | P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R22 |
| Safety Phrases | S26 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2932209090 |
Customs
| HS Code | 2932209090 |
|---|---|
| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles32
More Articles| Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, S-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole. Drug Metab. Dispos. 43 , 1408-16, (2015) The common marmoset (Callithrix jacchus), a small New World monkey, has the potential for use in human drug development due to its evolutionary closeness to humans. Four novel cDNAs, encoding cytochro... | |
| Investigation of two-dimensional high performance liquid chromatography approaches for reversed phase resolution of warfarin and hydroxywarfarin isomers. J. Chromatogr. A. 1363 , 200-6, (2014) Several offline and online 2D HPLC methods were investigated for the reversed phase resolution of a complex mixture of closely related warfarin and hydroxywarfarin isomers. By combining reversed phase... | |
| Hydroxywarfarin metabolites potently inhibit CYP2C9 metabolism of S-warfarin. Chem. Res. Toxicol. 23(5) , 939-45, (2010) Coumadin (R/S-warfarin) anticoagulant therapy poses a risk to over 50 million Americans, in part due to interpersonal variation in drug metabolism. Consequently, it is important to understand how meta... |
Synonyms
| 7-Hydroxywarfarin |
| 4,7-dihydroxy-3-(3-oxo-1-phenylbutyl)chromen-2-one |
