Introduction：Basic information about CAS 66148-78-5|temocillin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | temocillin |
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| CAS Number | 66148-78-5 | Molecular Weight | 414.45300 |
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| Density | 1.6 g/cm3 | Boiling Point | 761.9ºC at 760 mmHg |
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| Molecular Formula | C16H18N2O7S2 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | temocillin |
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| Synonym | More Synonyms |
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temocillin BiologicalActivity
| Description | Temocillin, a 6-alpha-methoxy penicillin derivative, is a semisynthetic beta-lactam antibiotic with a spectrum of activity against most aerobic Gram-negative bacteria[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| References | [1]. Alexandre K, et al. Pharmacokinetics and Pharmacodynamics of Temocillin. Clin Pharmacokinet. 2018 Mar;57(3):287-296. |
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Chemical & Physical Properties
| Density | 1.6 g/cm3 |
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| Boiling Point | 761.9ºC at 760 mmHg |
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| Molecular Formula | C16H18N2O7S2 |
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| Molecular Weight | 414.45300 |
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| Exact Mass | 414.05600 |
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| PSA | 186.78000 |
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| LogP | 0.85090 |
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| Index of Refraction | 1.675 |
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| InChIKey | BVCKFLJARNKCSS-DWPRYXJFSA-N |
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| SMILES | COC1(NC(=O)C(C(=O)O)c2ccsc2)C(=O)N2C(C(=O)O)C(C)(C)SC21 |
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Synonyms
| Temocilline [INN-French] |
| Temocillinum |
| Temocilline |
| Temocillina [INN-Spanish] |
| Temocillina |
| Temocillin |
| EINECS 266-184-1 |
| Temocillinum [INN-Latin] |
| (2S,5R,6S)-6-[(2-carboxy-2-thiophen-3-ylacetyl)amino]-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
