CAS 23669-79-6|5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine

Introduction：Basic information about CAS 23669-79-6|5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine
CAS Number	23669-79-6	Molecular Weight	530.56800
Density	1.294 g/cm3	Boiling Point	/
Molecular Formula	C₃₀H₃₀N₂O₇	Melting Point	/
MSDS	ChineseUSA	Flash Point	/
Symbol	GHS07	Signal Word	Warning

Names

Name	5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine
Synonym	More Synonyms

BiologicalActivity

Description	5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive inhibitor of E. coli dUTP nucleotidohydrolase (dUTPase), with the Ki higher than 1000 μM. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted DNA synthesis by synthesizing nucleosidic phosphoramidite blocks[1][2].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
Target	Ki: >1000 μM (E. coli dUTPase)[1]
References	[1]. Hidalgo-Zarco F, et, al. Kinetic properties and inhibition of the dimeric dUTPase-dUDPase from Leishmania major. Protein Sci. 2001 Jul;10(7):1426-33. [2]. Hovinen J, et, al. Versatile strategy for oligonucleotide derivatization. Introduction of lanthanide(III) chelates to oligonucleotides. Org Lett. 2001 Aug 9;3(16):2473-6.

Chemical & Physical Properties

Density	1.294 g/cm3
Molecular Formula	C₃₀H₃₀N₂O₇
Molecular Weight	530.56800
Exact Mass	530.20500
PSA	112.01000
LogP	3.21090
Appearance of Characters	Powder \| White to Off-white
Index of Refraction	1.61
InChIKey	BYGKUWPLEGHFKX-ZRRKCSAHSA-N
SMILES	COc1ccc(C(OCC2OC(n3ccc(=O)[nH]c3=O)CC2O)(c2ccccc2)c2ccc(OC)cc2)cc1
Storage condition	−20°C
Water Solubility	Soluble in acetonitrile at 20mg/ml

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H332-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R20/22;R36/37/38
Safety Phrases	S22-S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3

Synonyms

5'-O-[Bis(4-methoxyphenyl)benzyl]-2'-deoxyuridine

5'-O-Dimethylterephthale-2'-deoxyuridine

5'-(4,4'-dimethoxytrityl)-2'-deoxyuridine

5'-O-DMT-2'-DEOXYURIDINE

2'-deoxy-5'-O-dimethoxytrityluridine

DMT-DEOXYURIDINE

2'-deoxy-5'-(4,4'-dimethoxytrityl)uridine

5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxyuridine

dmt-du

2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-uridine

5'-O-(4,4'-dimetoxytrityl)-2'-deoxyuridine

2'-Deoxy-5'-O-DMT-uridine

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