Introduction：Basic information about CAS 76948-72-6|Cleomiscosin A, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Cleomiscosin A |
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| CAS Number | 76948-72-6 | Molecular Weight | 386.352 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 632.7±55.0 °C at 760 mmHg |
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| Molecular Formula | C20H18O8 | Melting Point | 245-247ºC |
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| MSDS | / | Flash Point | 228.5±25.0 °C |
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Names
| Name | cleomiscosin A |
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| Synonym | More Synonyms |
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Cleomiscosin A BiologicalActivity
| Description | Cleomiscosin A is a coumarino-lignoid from branch of Macaranga adenantha. Cleomiscosin A is active against TNF-alpha secretion of the mouse peritoneal macrophages[1][2]. |
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| Related Catalog | Research Areas >>Inflammation/Immunology |
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| Target | TNF-α |
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| References | [1]. Sharma S, et al. Synthesis and anti-inflammatory activity of derivatives of coumarino-lignoid, cleomiscosin A and its methyl ether. Eur J Med Chem. 2010;45(11):5150-5156. [2]. Ma M, et al. Zhongguo Zhong Yao Za Zhi. 2007;32(12):1175-1179. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 632.7±55.0 °C at 760 mmHg |
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| Melting Point | 245-247ºC |
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| Molecular Formula | C20H18O8 |
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| Molecular Weight | 386.352 |
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| Flash Point | 228.5±25.0 °C |
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| Exact Mass | 386.100159 |
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| PSA | 107.59000 |
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| LogP | 1.44 |
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| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
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| Index of Refraction | 1.618 |
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| InChIKey | OCBGWPJNUZMLCA-NVXWUHKLSA-N |
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| SMILES | COc1cc(C2Oc3c(OC)cc4ccc(=O)oc4c3OC2CO)ccc1O |
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Safety Information
Synonyms
| Cleomiscosin A |
| (2R,3R)-3-(4-Hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-2,3-dihydro-9H-[1,4]dioxino[2,3-h]chromen-9-one |
| 9H-Pyrano[2,3-f]-1,4-benzodioxin-9-one, 2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-, (2R,3R)- |
