Introduction：Basic information about CAS 108-29-2|γ-Valerolactone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | γ-Valerolactone |
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| CAS Number | 108-29-2 | Molecular Weight | 100.12 |
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| Density | 1.0±0.1 g/cm3 | Boiling Point | 206.6±8.0 °C at 760 mmHg |
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| Molecular Formula | C5H8O2 | Melting Point | -31ºC |
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| MSDS | ChineseUSA | Flash Point | 81.1±0.0 °C |
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Names
| Name | γ-valerolactone |
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| Synonym | More Synonyms |
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γ-Valerolactone BiologicalActivity
| Description | 5-Methyldihydrofuran-2(3H)-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
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| Related Catalog | Research Areas >>Others |
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| In Vitro | γ-戊内酯是一种分析参考标准品，被归类为 γ-羟基戊酸的前药形式。1 本产品旨在用于研究和法医应用。 |
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| References | [1]. Andresen-Streichert, H., Jungen, H., Gehl, A., et al. Uptake of gamma-valerolactone--detection of gamma-hydroxyvaleric acid in human urine samples. J. Anal. Toxicol. 37(4), 250-254 (2013). |
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Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
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| Boiling Point | 206.6±8.0 °C at 760 mmHg |
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| Melting Point | -31ºC |
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| Molecular Formula | C5H8O2 |
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| Molecular Weight | 100.12 |
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| Flash Point | 81.1±0.0 °C |
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| Exact Mass | 100.052429 |
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| PSA | 26.30000 |
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| LogP | -0.27 |
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| Vapour density | 3.45 (vs air) |
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| Vapour Pressure | 0.2±0.4 mmHg at 25°C |
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| Index of Refraction | 1.431 |
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| InChIKey | GAEKPEKOJKCEMS-UHFFFAOYSA-N |
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| SMILES | CC1CCC(=O)O1 |
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| Water Solubility | MISCIBLE |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- LU3580000
- CHEMICAL NAME :
- 2(3H)-Furanone, dihydro-5-methyl-
- CAS REGISTRY NUMBER :
- 108-29-2
- BEILSTEIN REFERENCE NO. :
- 0080420
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C5-H8-O2
- MOLECULAR WEIGHT :
- 100.13
- WISWESSER LINE NOTATION :
- T5O CVTJ E1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 8800 mg/kg
- TOXIC EFFECTS :
- Behavioral - general anesthetic Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory stimulation
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2480 mg/kg
- TOXIC EFFECTS :
- Behavioral - general anesthetic Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory stimulation
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 2500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 gm/m3/7H/92D-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
MUTATION DATA - TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TEST SYSTEM :
- Yeast - Saccharomyces cerevisiae
- DOSE/DURATION :
- 24400 ppm
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 201,431,1988
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Safety Information
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
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| Hazard Codes | Xi:Irritant; |
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| Risk Phrases | R36 |
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| Safety Phrases | S26-S39 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 2 |
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| RTECS | LU3580000 |
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| Packaging Group | I; II; III |
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| HS Code | 29322980 |
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Customs
| HS Code | 2932209090 |
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| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| γ-Valeryllactone |
| Pentanoic acid, 4-hydroxy-, .γ.-lactone |
| gamma-valerolactone |
| 2(3H)-Furanone, dihydro-5-methyl- |
| (±)-4-Methylbutyrolactone |
| 4-Valerolactone |
| Dihydro-5-methyl-2(3H)-furanone |
| 4,5-Dihydro-5-methyl-2(3H)-furanone |
| (±)-γ-Valerolactone |
| Valeric acid, 4-hydroxy-, γ-lactone |
| EINECS 203-569-5 |
| Valerolactone |
| Pentanoic acid, 4-hydroxy-, γ-lactone |
| 5-methyldihydrofuran-2(3H)-one |
| 2(3H)-Furanone, dihydro-5-methyl-, (±)- |
| 5-Methyldihydro-2(3H)-furanone |
| furan-2-one, 5-methyltetrahydro- |
| dihydro-5-methyl-2(3H)-furanone, |
| γ-Valerolactone |
| MFCD00005400 |
