CAS 4663-83-6|Carbamic acid,N-(phenylmethyl)-, 2-hydroxyethyl ester

Introduction:Basic information about CAS 4663-83-6|Carbamic acid,N-(phenylmethyl)-, 2-hydroxyethyl ester, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameCarbamic acid,N-(phenylmethyl)-, 2-hydroxyethyl ester
CAS Number4663-83-6Molecular Weight195.21500
Density1.182 g/cm3Boiling Point375.8ºC at 760mmHg
Molecular FormulaC10H13NO3Melting Point/
MSDS/Flash Point181.1ºC

Names

Name2-hydroxyethyl N-benzylcarbamate
SynonymMore Synonyms

BiologicalActivity

DescriptionBuramate exhibits neuroprotective and anticonvulsant activities.
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease

Chemical & Physical Properties

Density1.182 g/cm3
Boiling Point375.8ºC at 760mmHg
Molecular FormulaC10H13NO3
Molecular Weight195.21500
Flash Point181.1ºC
Exact Mass195.09000
PSA58.56000
LogP1.29600
Index of Refraction1.542
InChIKeyYFLRYAVDPKONNX-UHFFFAOYSA-N
SMILESO=C(NCc1ccccc1)OCCO

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EY8747000
CHEMICAL NAME :
Carbamic acid, benzyl-, 2-hydroxyethyl ester
CAS REGISTRY NUMBER :
4663-83-6
BEILSTEIN REFERENCE NO. :
2838813
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H13-N-O3
MOLECULAR WEIGHT :
195.24
WISWESSER LINE NOTATION :
Q2OVM1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
850 mg/kg
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Behavioral - changes in motor activity (specific assay) Behavioral - antipsychotic
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 127,220,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 9,390,1951

Safety Information

HS Code2924299090

Customs

HS Code2924299090
Summary2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synonyms

AC-601
Buramate
Hyamate
Buramat
2-Benzylcarbamoyloxy-aethanol
2-Hydroxyethyl benzylcarbamate
CAS 478827-76-8|N-[1-(Cyclohexylmethyl)-4-piperidinyl]-1H-indazole-5-carboxamide
CAS 478827-75-7|N-[1-(Cyclopropylmethyl)-4-piperidinyl]-1H-indazole-5-carboxamide
Recommended......
TOP