Introduction：Basic information about CAS 69256-17-3|2'-Fluoro-5-methylarabinosyluracil, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2'-Fluoro-5-methylarabinosyluracil |
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| CAS Number | 69256-17-3 | Molecular Weight | 260.22 |
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| Density | 1.6±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C10H13FN2O5 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil |
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| Synonym | More Synonyms |
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2'-Fluoro-5-methylarabinosyluracil BiologicalActivity
| Description | FMAU is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others |
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| References | [1]. Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93. |
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Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
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| Molecular Formula | C10H13FN2O5 |
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| Molecular Weight | 260.22 |
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| Exact Mass | 260.080841 |
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| PSA | 104.55000 |
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| LogP | -0.72 |
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| Index of Refraction | 1.593 |
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| InChIKey | GBBJCSTXCAQSSJ-JVZYCSMKSA-N |
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| SMILES | Cc1cn(C2OC(CO)C(O)C2F)c(=O)[nH]c1=O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- YQ9512600
- CHEMICAL NAME :
- Uracil, 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyl -
- CAS REGISTRY NUMBER :
- 69256-17-3
- LAST UPDATED :
- 198303
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C10-H13-F-N2-O5
- MOLECULAR WEIGHT :
- 260.25
- WISWESSER LINE NOTATION :
- T6NVMVJ E1 A- BT5OTJ CF DQ E1Q
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA - TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - mouse Leukocyte
- DOSE/DURATION :
- 17 umol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 42,3957,1982
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Safety Information
Customs
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione |
| 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyluracil |
| 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyl- |
| 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione |
