Introduction:Basic information about CAS 101187-40-0|PROTAC Linker 15, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | PROTAC Linker 15 |
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| CAS Number | 101187-40-0 | Molecular Weight | 292.37200 |
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| Density | 1.05 | Boiling Point | / |
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| Molecular Formula | C13H28N2O5 | Melting Point | / |
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| MSDS | Chinese | Flash Point | / |
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Names
| Name | tert-butyl N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]carbamate |
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| Synonym | More Synonyms |
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PROTAC Linker 15 BiologicalActivity
| Description | PROTAC Linker 15 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 15 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | Alkyl/ether |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
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Chemical & Physical Properties
| Density | 1.05 |
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| Molecular Formula | C13H28N2O5 |
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| Molecular Weight | 292.37200 |
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| Exact Mass | 292.20000 |
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| PSA | 92.04000 |
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| LogP | 1.61080 |
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| InChIKey | CUPBLDPRUBNAIE-UHFFFAOYSA-N |
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| SMILES | CC(C)(C)OC(=O)NCCOCCOCCOCCN |
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2924199090 |
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Customs
| HS Code | 2924199090 |
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| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| t-Boc-N-Amido-PEG3-Amine |
| 13-AMINO-5,8,11-TRIOXA-2-AZATRIDECANOIC ACID 1,1-DIMETHYLETHYL ESTER |
| 1-Boc-amine-11-amino-3,6,9-trioxaundecane |