CAS 101187-40-0|PROTAC Linker 15

Introduction:Basic information about CAS 101187-40-0|PROTAC Linker 15, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NamePROTAC Linker 15
CAS Number101187-40-0Molecular Weight292.37200
Density1.05Boiling Point/
Molecular FormulaC13H28N2O5Melting Point/
MSDSChineseFlash Point/

Names

Nametert-butyl N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]carbamate
SynonymMore Synonyms

PROTAC Linker 15 BiologicalActivity

DescriptionPROTAC Linker 15 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 15 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

Alkyl/ether

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Chemical & Physical Properties

Density1.05
Molecular FormulaC13H28N2O5
Molecular Weight292.37200
Exact Mass292.20000
PSA92.04000
LogP1.61080
InChIKeyCUPBLDPRUBNAIE-UHFFFAOYSA-N
SMILESCC(C)(C)OC(=O)NCCOCCOCCOCCN

Safety Information

Hazard CodesXi
HS Code2924199090

Customs

HS Code2924199090
Summary2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synonyms

t-Boc-N-Amido-PEG3-Amine
13-AMINO-5,8,11-TRIOXA-2-AZATRIDECANOIC ACID 1,1-DIMETHYLETHYL ESTER
1-Boc-amine-11-amino-3,6,9-trioxaundecane
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