CAS 76880-29-0|Boc-Cys(NPys)-OH

Introduction:Basic information about CAS 76880-29-0|Boc-Cys(NPys)-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameBoc-Cys(NPys)-OH
CAS Number76880-29-0Molecular Weight375.421
Density1.4±0.1 g/cm3Boiling Point553.9±50.0 °C at 760 mmHg
Molecular FormulaC13H17N3O6S2Melting Point-160ºC (dec.)
MSDSChineseUSAFlash Point288.8±30.1 °C

Names

Name(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[(3-nitropyridin-2-yl)disulfanyl]propanoic acid
SynonymMore Synonyms

Boc-Cys(NPys)-OH BiologicalActivity

DescriptionBoc-Cys(Npys)-OH is a cysteine derivative[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
In VitroAmino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807.

Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point553.9±50.0 °C at 760 mmHg
Melting Point-160ºC (dec.)
Molecular FormulaC13H17N3O6S2
Molecular Weight375.421
Flash Point288.8±30.1 °C
Exact Mass375.055878
PSA184.94000
LogP4.25
Vapour Pressure0.0±1.6 mmHg at 25°C
Index of Refraction1.616
InChIKeyOVTLOLNDKQUMRH-QMMMGPOBSA-N
SMILESCC(C)(C)OC(=O)NC(CSSc1ncccc1[N+](=O)[O-])C(=O)O

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases22-24/25
RIDADRNONH for all modes of transport

Articles4

More Articles
Controlled peptide-protein conjugation by means of 3-nitro-2-pyridinesulfenyl protection-activation.

Int. J. Pept. Protein Res. 32(3) , 161-6, (1988)

The disulfide bond in S-3-nitro-2-pyridinesulfenyl (S-Npys) compounds is stable towards the acid treatment used in solid-phase peptide synthesis, yet the liability of S-Npys-peptides towards nucleophi...

Preparation of Boc-[S-(3-nitro-2-pyridinesulfenyl)]-cysteine and its use for unsymmetrical disulfide bond formation.

Int. J. Pept. Protein Res. 28(2) , 107-12, (1986)

The 3-nitro-2-pyridinesulfenyl (Npys) derivative of cysteine was prepared and used to facilitate the formation of an unsymmetrical disulfide bond. Since this derivative is stable in trifluoroacetic ac...

Effects of sulfhydryl-modifying reagents, 3-nitro-2-pyridinesulfenyl compounds, on the coupling between inhibitory receptors and GTP-binding proteins Gi/Go in rat brain membranes.

Mol. Pharmacol. 38(2) , 184-91, (1990)

To gain insight into the coupling mechanism of inhibitory receptors, 5-hydroxytryptamine1A receptors and alpha 2-adrenoceptors, with GTP-binding proteins (G proteins) in the central nervous system, we...

Synonyms

N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-3-[(3-nitro-2-pyridinyl)disulfanyl]-L-alanine
n-(tert-butoxycarbonyl)-3-[(3-nitropyridin-2-yl)disulfanyl]-l-alanine
Boc-Cys-S-(3-nitro-2-pyridinesulfenyl)
Boc-cys(npys)
N-t-butoxycarbonyl-S-(3-nitro-2-pyridylthio)-L-cysteine
t-Bcnp
Boc-cys(npys)-OH
MFCD00153301
L-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-3-[(3-nitro-2-pyridinyl)dithio]-
Nalpha-Boc-S-(3-nitro-2-pyridylthio)-L-cysteine
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