Introduction：Basic information about CAS 28342-33-8|6-Oxochelerythrine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 6-Oxochelerythrine |
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| CAS Number | 28342-33-8 | Molecular Weight | 363.36 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 615.5±55.0 °C at 760 mmHg |
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| Molecular Formula | C21H17NO5 | Melting Point | / |
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| MSDS | / | Flash Point | 326.1±31.5 °C |
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Names
| Name | 1,2-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-13-one |
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| Synonym | More Synonyms |
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6-Oxochelerythrine BiologicalActivity
| Description | Oxychelerythrine is an alkaloid that can be isolated from Zanthoxylum integrifoliolum. Oxychelerythrine exhibits cytotoxicity against P-388 and HT-29 cell lines with ED50s of 3.25 and 5.48 μg/mL, respectively[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| References | [1]. Chen, J.-J., et al. New Indolopyridoquinazoline, Benzo[c]phenanthridines and Cytotoxic Constituents fromZanthoxylum integrifoliolum . Planta Medica, 71(5), 470–475. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 615.5±55.0 °C at 760 mmHg |
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| Molecular Formula | C21H17NO5 |
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| Molecular Weight | 363.36 |
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| Flash Point | 326.1±31.5 °C |
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| Exact Mass | 363.110687 |
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| PSA | 58.92000 |
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| LogP | 3.38 |
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| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
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| Index of Refraction | 1.669 |
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| InChIKey | IHTXRYTWDARUKX-UHFFFAOYSA-N |
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| SMILES | COc1ccc2c(c1OC)c(=O)n(C)c1c3cc4c(cc3ccc21)OCO4 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- FL9220000
- CHEMICAL NAME :
- Chelerythrine, 12,13-dihydro-13-oxo-
- CAS REGISTRY NUMBER :
- 28342-33-8
- BEILSTEIN REFERENCE NO. :
- 0345198
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C21-H17-N-O5
- MOLECULAR WEIGHT :
- 363.39
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA - TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 125 ug/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 240,267,1990
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Safety Information
Synonyms
| oxotoddaline |
| [1,3]Benzodioxolo[5,6-c]phenanthridin-13(12H)-one, 1,2-dimethoxy-12-methyl- |
| Oxychelerythrine |
| oxychelerytrine |
| Dihydrooxochelerythrine |
| Chelerythrine,12,13-dihydro-13-oxo |
| 1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-13(12H)-one |
| 6-Oxochelerythrine |
