Introduction：Basic information about CAS 48236-96-0|3",8"-Binaringenin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 3",8"-Binaringenin |
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| CAS Number | 48236-96-0 | Molecular Weight | 542.490 |
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| Density | 1.6±0.1 g/cm3 | Boiling Point | 932.8±65.0 °C at 760 mmHg |
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| Molecular Formula | C30H22O10 | Melting Point | / |
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| MSDS | / | Flash Point | 314.3±27.8 °C |
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Names
| Name | (2S)-8-{5-[(2S)-5,7-Dihydroxy-4-oxo-3,4-dihydro-2H-chromen-2-yl]- 2-hydroxyphenyl}-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H -chromen-4-one |
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| Synonym | More Synonyms |
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3",8"-Binaringenin BiologicalActivity
| Description | Tetrahydroamentoflavone (Amentoflavanone) is a potent xanthine oxidase (XO) inhibitor. Tetrahydroamentoflavone has inhibitory activity for XO with IC50 and Ki values of 92 nM and 0.982 μM, respectively. Tetrahydroamentoflavone can be used for the research of inflammatory disorders and gout[1]. |
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| Related Catalog | Research Areas >>InfectionResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Metabolic Enzyme/Protease >>Xanthine Oxidase |
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| Target | IC50: 92 nM (XO)[1]. Ki: 0.982 μM (XO)[1]. |
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| In Vitro | Tetrahydroamentoflavone 对 XO 具有抑制活性，IC50 和 Ki 值分别为 92 nM 和 0.982 μM[1]。 |
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| References | [1]. Ranjith Arimboor, et al. Tetrahydroamentoflavone (THA) from Semecarpus anacardium as a potent inhibitor of xanthine oxidase. J Ethnopharmacol. 2011 Feb 16;133(3):1117-20. |
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Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
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| Boiling Point | 932.8±65.0 °C at 760 mmHg |
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| Molecular Formula | C30H22O10 |
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| Molecular Weight | 542.490 |
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| Flash Point | 314.3±27.8 °C |
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| Exact Mass | 542.121277 |
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| PSA | 173.98000 |
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| LogP | 5.03 |
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| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
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| Index of Refraction | 1.745 |
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| InChIKey | ULTQJSQDLWNWTR-UHFFFAOYSA-N |
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| SMILES | O=C1CC(c2ccc(O)c(-c3c(O)cc(O)c4c3OC(c3ccc(O)cc3)CC4=O)c2)Oc2cc(O)cc(O)c21 |
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Safety Information
Synonyms
| 8-[5-(5,7-Dihydroxy-4-oxo-3,4-dihydro-2H-chromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one |
| 3",8"-Binaringenin |
| 4H-1-Benzopyran-4-one, 8-[5-(3,4-dihydro-5,7-dihydroxy-4-oxo-2H-1-benzopyran-2-yl)-2-hydroxyphenyl]-2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)- |
