Introduction：Basic information about CAS 1092578-46-5|(3R,4S)-Tofacitinib, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (3R,4S)-Tofacitinib |
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| CAS Number | 1092578-46-5 | Molecular Weight | 312.370 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 585.8±50.0 °C at 760 mmHg |
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| Molecular Formula | C16H20N6O | Melting Point | / |
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| MSDS | / | Flash Point | 308.1±30.1 °C |
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Names
| Name | 3-[(3R,4S)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile |
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| Synonym | More Synonyms |
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(3R,4S)-Tofacitinib BiologicalActivity
| Description | (3R,4S)-Tofacitinib is an enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM. |
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| Related Catalog | Research Areas >>Inflammation/Immunology |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 585.8±50.0 °C at 760 mmHg |
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| Molecular Formula | C16H20N6O |
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| Molecular Weight | 312.370 |
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| Flash Point | 308.1±30.1 °C |
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| Exact Mass | 312.169861 |
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| PSA | 88.91000 |
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| LogP | 0.93 |
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| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
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| Index of Refraction | 1.646 |
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| InChIKey | UJLAWZDWDVHWOW-AAEUAGOBSA-N |
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| SMILES | CC1CCN(C(=O)CC#N)CC1N(C)c1ncnc2[nH]ccc12 |
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| Storage condition | -20°C |
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Synonyms
| (3R,4S)-Tofacitinib| |
| CS-1109 |
| 1-Piperidinepropanenitrile,4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)--oxo-,(3R,4S) |
| 3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile |
| 3-((3R,4S)-3-((1H-Indol-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropan-enitrile |
| (3R,4S)-Tofacitinib |
