CAS 891494-64-7|MK-8776

Introduction：Basic information about CAS 891494-64-7|MK-8776, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. MK-8776 BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	MK-8776
CAS Number	891494-64-7	Molecular Weight	376.254
Density	1.8±0.1 g/cm3	Boiling Point	/
Molecular Formula	C₁₅H₁₈BrN₇	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	6-bromo-3-(1-methylpyrazol-4-yl)-5-[(3S)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine
Synonym	More Synonyms

MK-8776 BiologicalActivity

Description	SCH900776 S-isomer is the S-isomer of SCH900776. SCH900776 is a potent, selective and orally bioavailable inhibitor of checkpoint kinase1 (Chk1) with IC50 of 3 nM.
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Cancer

Chemical & Physical Properties

Density	1.8±0.1 g/cm3
Molecular Formula	C₁₅H₁₈BrN₇
Molecular Weight	376.254
Exact Mass	375.080688
PSA	86.06000
LogP	0.76
Index of Refraction	1.819
InChIKey	GMIZZEXBPRLVIV-VIFPVBQESA-N
SMILES	Cn1cc(-c2cnn3c(N)c(Br)c(C4CCCNC4)nc23)cn1
Storage condition	2-8℃

Synonyms

6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-[(3S)-3-piperidinyl]pyrazolo[1,5-a]pyrimidin-7-amine

Pyrazolo[1,5-a]pyrimidin-7-amine, 6-bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-[(3R)-3-piperidinyl]-

CS-1119

6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-((3S)-piperidin-3-yl)pyrazolo(1,5-a)pyrimidin-7-amine

Pyrazolo(1,5-a)pyrimidin-7-amine,6-bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-(3S)-3-piperidinyl

UNII-99Y1V29WVE

6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-[(3R)-3-piperidinyl]pyrazolo[1,5-a]pyrimidin-7-amine

Pyrazolo[1,5-a]pyrimidin-7-amine, 6-bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-[(3S)-3-piperidinyl]-

MK-8776

SCH 900776

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