Introduction：Basic information about CAS 106900-12-3|Loperamide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Loperamide |
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| CAS Number | 106900-12-3 | Molecular Weight | 493.03700 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C29H33ClN2O3 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 4-[4-(4-chlorophenyl)-4-hydroxy-1-oxidopiperidin-1-ium-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Molecular Formula | C29H33ClN2O3 |
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| Molecular Weight | 493.03700 |
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| Exact Mass | 492.21800 |
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| PSA | 69.97000 |
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| LogP | 5.05940 |
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| InChIKey | KXVSBTJVTUVNPM-UHFFFAOYSA-N |
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| SMILES | CN(C)C(=O)C(CC[N+]1([O-])CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 |
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| Water Solubility | Practically insoluble in water, freely soluble in alcohol and in methylene chloride. |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- TM4960200
- CHEMICAL NAME :
- 1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha -diphenyl-, 1-oxide, (E)-
- CAS REGISTRY NUMBER :
- 106900-12-3
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C29-H33-Cl-N2-O3
- MOLECULAR WEIGHT :
- 493.09
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 172 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DDREDK Drug Development Research. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1981- Volume(issue)/page/year: 8,279,1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 28300 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DDREDK Drug Development Research. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1981- Volume(issue)/page/year: 8,279,1986
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Safety Information
| RIDADR | UN 2811 6.1 / PGIII |
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| RTECS | TM4960200 |
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Synonyms
| Loperamide N-oxide |
| Loperamide oxide |
| trans-N-Oxide of loperamide |
| Arestal |
