CAS 24358-84-7|Dexivacaine

Introduction:Basic information about CAS 24358-84-7|Dexivacaine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameDexivacaine
CAS Number24358-84-7Molecular Weight246.35
Density1.077g/cm3Boiling Point383.1ºC at 760mmHg
Molecular FormulaC15H22N2OMelting Point/
MSDS/Flash Point185.5ºC

Names

Name(2S)-N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide
SynonymMore Synonyms

Dexivacaine BiologicalActivity

Description(+)-Mepivacaine is a racemic isomer of Mepivacaine (HY-B0517), which has analgesic and vasoconstrictive activity. Mepivacaine is an amide type agent that temporarily causes local loss of consciousness. Mepivacaine binds to specific voltage-gated sodium channels on neuronal cell membranes, inhibiting sodium influx and membrane depolarization[1].
Related CatalogResearch Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>Others
References

[1]. Fairley J W, et al. An intradermal study of the local anaesthetic and vascular effects of the isomers of mepivacaine[J]. British Journal of Anaesthesia, 1981, 53(11): 1211-1216.

Chemical & Physical Properties

Density1.077g/cm3
Boiling Point383.1ºC at 760mmHg
Molecular FormulaC15H22N2O
Molecular Weight246.35
Flash Point185.5ºC
Exact Mass246.17300
PSA35.83000
LogP3.31360
Vapour Pressure4.52E-06mmHg at 25°C
Index of Refraction1.567
InChIKeyINWLQCZOYSRPNW-ZDUSSCGKSA-N
SMILESCc1cccc(C)c1NC(=O)C1CCCCN1C

Synonyms

Dexivacainum [INN-Latin]
(+)-Mepivacaine
Dexivacain
DEXIVACAINE
Dexivacaine [USAN:INN]
2',6'-Pipecoloxylidide,1-methyl-,L-(+)
(+)-1-Methyl-2',6'-pipecoloxylidide
(S)-Mepivacaine
Dexivacaina [INN-Spanish]
L(+)-Mepivacaine
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