CAS 23403-54-5|alpha-D-glucose-d7

Introduction:Basic information about CAS 23403-54-5|alpha-D-glucose-d7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Namealpha-D-glucose-d7
CAS Number23403-54-5Molecular Weight187.19900
Density1.799g/cm3Boiling Point410.8ºC at 760 mmHg
Molecular FormulaC6H5D7O6Melting Point150-152ºC(lit.)
MSDSUSAFlash Point202.2ºC

Names

NameD-Glucose-C-d7, Deuterated Glucose, Dextrose-C-d7, Labeled Glucose
SynonymMore Synonyms

alpha-D-glucose-d7 BiologicalActivity

Descriptionalpha-D-glucose-d7 is the deuterium labeled alpha-D-glucose[1]. alpha-D-glucose is an endogenous metabolite.
Related CatalogResearch Areas >>Metabolic Disease
In VitroStable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

Density1.799g/cm3
Boiling Point410.8ºC at 760 mmHg
Melting Point150-152ºC(lit.)
Molecular FormulaC6H5D7O6
Molecular Weight187.19900
Flash Point202.2ºC
Exact Mass187.10700
PSA110.38000
Vapour Pressure1.83E-08mmHg at 25°C
Index of Refraction1.635
InChIKeyWQZGKKKJIJFFOK-QCQRZMBHSA-N
SMILESOCC1OC(O)C(O)C(O)C1O

Safety Information

Safety PhrasesS22-S24/25
RIDADRNONH for all modes of transport

Synonyms

MFCD00144081
D-Glucose-1,2,3,4,5,6,6-d7
(3R,4S,5S,6S)-2,3,4,5,6-pentadeuterio-6-[dideuterio(hydroxy)methyl]oxane-2,3,4,5-tetrol
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