Introduction：Basic information about CAS 525-21-3|Fraxidin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Fraxidin |
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| CAS Number | 525-21-3 | Molecular Weight | 222.194 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 424.2±45.0 °C at 760 mmHg |
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| Molecular Formula | C11H10O5 | Melting Point | 196-197ºC |
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| MSDS | / | Flash Point | 171.0±22.2 °C |
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Names
| Name | 8-hydroxy-6,7-dimethoxychromen-2-one |
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| Synonym | More Synonyms |
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Fraxidin BiologicalActivity
| Description | Fraxidin is a class of coumarin isolated from the roots of Jatropha podagrica, exhibits antibacterial activity against Bacillus subtilis with an inhibition zone of 12 mm at a concentration of 20 µg/disk[1][2]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| Target | Bacillus subtilis[2] |
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| References | [1]. Kim NY, et al. In vitro inducible nitric oxide synthesis inhibitory active constituents from Fraxinus rhynchophylla. Planta Med. 1999 Oct;65(7):656-8. [2]. Minh TN, et al. Isolation and Purification of Bioactive Compounds from the Stem Bark of Jatropha podagrica. Molecules. 2019 Mar 3;24(5). pii: E889. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 424.2±45.0 °C at 760 mmHg |
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| Melting Point | 196-197ºC |
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| Molecular Formula | C11H10O5 |
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| Molecular Weight | 222.194 |
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| Flash Point | 171.0±22.2 °C |
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| Exact Mass | 222.052826 |
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| PSA | 68.90000 |
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| LogP | 0.56 |
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| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
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| Index of Refraction | 1.588 |
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| InChIKey | QNFBKOHHLAWWTC-UHFFFAOYSA-N |
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| SMILES | COc1cc2ccc(=O)oc2c(O)c1OC |
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2932209090 |
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Customs
| HS Code | 2932209090 |
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| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| EINECS 208-370-7 |
| 8-hydroxy-6,7,-dimethoxycoumarin |
| 8-Hydroxy-6,7-dimethoxy-cumarin |
| 6,7-dimethoxy-8-hydroxy-2H-1-benzopyran-2-one |
| 8-hydroxy-6,7-dimethoxy-2-benzopyrone |
| 6,7-dimethoxy-8-hydroxycoumarin |
| 8-Hydroxy-6,7-dimethoxy-2H-chromen-2-one |
| Fraxidin |
| 2H-1-Benzopyran-2-one, 8-hydroxy-6,7-dimethoxy- |
| 6,7,8-Trihydroxycoumarin 6,7-dimethyl ether |
