CAS 93-35-6|7-Hydroxycoumarine
| Common Name | 7-Hydroxycoumarine | ||
|---|---|---|---|
| CAS Number | 93-35-6 | Molecular Weight | 162.142 |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 382.1±37.0 °C at 760 mmHg |
| Molecular Formula | C9H6O3 | Melting Point | 230 °C (dec.)(lit.) |
| MSDS | ChineseUSA | Flash Point | 181.2±19.3 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | umbelliferone |
|---|---|
| Synonym | More Synonyms |
7-Hydroxycoumarine BiologicalActivity
| Description | Umbelliferone, a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. |
|---|---|
| Related Catalog | Natural Products >>PhenylpropanoidsResearch Areas >>Others |
| Target | Human Endogenous Metabolite |
| References | [1]. Yu SM, et al. Umbelliferone exhibits anticancer activity via the induction of apoptosis and cell cycle arrest in HepG2 hepatocellular carcinoma cells. Mol Med Rep. 2015 Sep;12(3):3869-3873. |
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 382.1±37.0 °C at 760 mmHg |
| Melting Point | 230 °C (dec.)(lit.) |
| Molecular Formula | C9H6O3 |
| Molecular Weight | 162.142 |
| Flash Point | 181.2±19.3 °C |
| Exact Mass | 162.031693 |
| PSA | 50.44000 |
| LogP | 1.58 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.640 |
| InChIKey | ORHBXUUXSCNDEV-UHFFFAOYSA-N |
| SMILES | O=c1ccc2ccc(O)cc2o1 |
| Storage condition | -20°C Freezer |
| Water Solubility | 1 g/100 mL (100 ºC) |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 450 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA - TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Klebsiella pneumoniae
- DOSE/DURATION :
- 800 mg/L
- REFERENCE :
- JIMMBG Journal of Immunological Methods. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1971- Volume(issue)/page/year: 36,55,1980
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Klebsiella pneumoniae
- DOSE/DURATION :
- 800 mg/L
- REFERENCE :
- JIMMBG Journal of Immunological Methods. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1971- Volume(issue)/page/year: 36,55,1980
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | GN6820000 |
| HS Code | 29322980 |
Customs
| HS Code | 2932209090 |
|---|---|
| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| UMBELLIFERON |
| 2H-1-Benzopyran-2-one, 7-hydroxy- |
| Hydrangine |
| Umbelliferone |
| Hydramgin |
| 7-Hydroxy-2H-chromen-2-one |
| Dichrin A |
| 7-hydroxy-2H-1-benzopyran-2-one |
| EINECS 202-240-3 |
| Skimmetine |
| umberlliferone |
| SKIMMETIN |
| 7-Hydroxycoumarin |
| 7-hydroxy-coumarin |
| 7-hydroxy-coumarine |
| MFCD01861511 |
| hydrangin |
| 7 HC |
