CAS 2459-05-4|Monoethyl fumarate
| Common Name | Monoethyl fumarate | ||
|---|---|---|---|
| CAS Number | 2459-05-4 | Molecular Weight | 144.125 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 147 ºC (16 mmHg) |
| Molecular Formula | C6H8O4 | Melting Point | 64-69 ºC |
| MSDS | ChineseUSA | Flash Point | 109.6±16.1 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | Monoethyl fumarate |
|---|---|
| Synonym | More Synonyms |
Monoethyl fumarate BiologicalActivity
| Description | Monoethyl fumarate is the monoethyl ester form of fumaric acid. Monoethyl fumarate is a kind of effective preservative and polymerization agent for macromolecular material[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. Ausama Atwan, et al. Oral Fumaric Acid Esters for Psoriasis. Cochrane Database Syst Rev. 2015 Aug 10;2015(8):CD010497. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 147 ºC (16 mmHg) |
| Melting Point | 64-69 ºC |
| Molecular Formula | C6H8O4 |
| Molecular Weight | 144.125 |
| Flash Point | 109.6±16.1 °C |
| Exact Mass | 144.042252 |
| PSA | 63.60000 |
| LogP | 0.29 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.469 |
| Storage condition | Refrigerator |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 1 |
| HS Code | 2918990090 |
Customs
| HS Code | 2918990090 |
|---|---|
| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Articles28
More Articles| Structure-activity relationships of trans-substituted-propenoic acid derivatives on the nicotinic acid receptor HCA2 (GPR109A). Bioorg. Med. Chem. Lett. 21 , 2736-9, (2011) Nicotinic acid (niacin) has been used for decades as an antidyslipidemic drug in man. Its main target is the hydroxy-carboxylic acid receptor HCA2 (GPR109A), a G protein-coupled receptor. Other acids ... | |
| Fumarate analogs act as allosteric inhibitors of the human mitochondrial NAD(P)+-dependent malic enzyme. PLoS ONE 9(6) , e98385, (2014) Human mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME) is allosterically activated by the four-carbon trans dicarboxylic acid, fumarate. Previous studies have suggested that the dicarboxylic... | |
| The use of differential transverse relaxation to detect mobile species in solids. Solid State Nucl. Magn. Reson. 6(1) , 63-71, (1996) Delayed acquisition of the proton NMR in selected organic molecular solids (L-alanine, durene, ethyl fumarate, and p-hydroxybenzoic acid) is shown to allow the observation of mobile species in the pre... |
Synonyms
| Ethyl fumaric acid |
| 2-Butenedioic acid, monoethyl ester, (2E)- |
| ETHYL ACID FUMARATE |
| Fumaric acid monoethyl ester |
| Monoethyl FuMerate |
| Ethyl fumarate |
| mono-Ethyl Fumarate |
| (2E)-4-Ethoxy-4-oxo-2-butenoic acid |
| RARECHEM AL BE 1505 |
| Ethyl Hydrogen Fumarate |
| FuMaric Acid Ethyl Ester |
| Ethylfumarat |
| (2E)-4-ethoxy-4-oxobut-2-enoic acid |
| EINECS 219-544-7 |
| Monoethyl FuMarate |
| monoethyl fumaric acid |
| MFCD00002699 |
| (E)-4-Ethoxy-4-oxobut-2-enoic acid |
| ETHYL FUMARATE MONOESTER |
| Quetiapine Impurity 33 |
