CAS 2457-76-3|2-Chloro-p-aminobenzoic acid
Introduction：Basic information about CAS 2457-76-3|2-Chloro-p-aminobenzoic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Chloro-p-aminobenzoic acid | ||
|---|---|---|---|
| CAS Number | 2457-76-3 | Molecular Weight | 171.581 |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 365.3±27.0 °C at 760 mmHg |
| Molecular Formula | C7H6ClNO2 | Melting Point | 211 °C (dec.)(lit.) |
| MSDS | ChineseUSA | Flash Point | 174.8±23.7 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 4-amino-2-chlorobenzoic acid |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 365.3±27.0 °C at 760 mmHg |
| Melting Point | 211 °C (dec.)(lit.) |
| Molecular Formula | C7H6ClNO2 |
| Molecular Weight | 171.581 |
| Flash Point | 174.8±23.7 °C |
| Exact Mass | 171.008713 |
| PSA | 63.32000 |
| LogP | 1.26 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.649 |
| InChIKey | MBDUKNCPOPMRJQ-UHFFFAOYSA-N |
| SMILES | Nc1ccc(C(=O)O)c(Cl)c1 |
| Storage condition | −20°C |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA - TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 500 mg/L
- REFERENCE :
- JGMIAN Journal of General Microbiology. (Soc. for General Microbiology, Journal Sales, 62 London Rd., Reading, RG1 5AS, UK) V.1- 1947- Volume(issue)/page/year: 18,543,1958
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 500 mg/L
- REFERENCE :
- JGMIAN Journal of General Microbiology. (Soc. for General Microbiology, Journal Sales, 62 London Rd., Reading, RG1 5AS, UK) V.1- 1947- Volume(issue)/page/year: 18,543,1958
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | DG1575000 |
| HS Code | 29224995 |
Customs
| HS Code | 2922499990 |
|---|---|
| Summary | HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |
Articles8
More Articles| Validation of high-performance liquid chromatographic methods on two silica base-deactivated reversed phases for the determination of chloroprocaine and bupivacaine. J. Pharm. Biomed. Anal. 14(8-10) , 1251-9, (1996) The separation of HPLC of basic drugs on silica-based reversed phases remains a major problem because of the interaction between the residual silanol groups of the silica and the amino function of the... | |
| Intrapartum paracervical block anesthesia with 2-chloroprocaine. Am. J. Obstet. Gynecol. 146(1) , 16-22, (1983) Most of the reports of fetal bradycardia and acidosis following paracervical block anesthesia have involved the use of amide-linked anesthetics, such as lidocaine and mepivacaine. The purposes of this... | |
| Comparison of lidocaine and 2-chloroprocaine in paracervical block: clinical effects and drug concentrations in mother and child. Anesth. Analg. 62(2) , 168-73, (1983) 2-Chloroprocaine (CP) has recently been recommended as a less toxic alternative to amide-type local anesthetics due to its rapid metabolism. A double-blind, randomized study comparing CP to lidocaine ... |
Synonyms
| 4-Amino-2-chlorobenzoic acid |
| Benzoic acid, 4-amino-2-chloro- |
| EINECS 219-540-5 |
| 4-amino-2-chloro-benzoic acid |
| 4-Amino-2-chlor-benzoesaeure |
| o-Chloro-p-aminobenzoic acid |
| Benzoic acid,4-amino-2-chloro |
| 2-Chloro-4-aminobenzoic acid |
| MFCD03407960 |
| 2-Chloro-p-aminobenzoic acid |
| USAF NB-1 |
