Introduction：Basic information about CAS 101328-85-2|OR-1855, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | OR-1855 |
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| CAS Number | 101328-85-2 | Molecular Weight | 203.240 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C11H13N3O | Melting Point | 206-208ºC |
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| MSDS | / | Flash Point | / |
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Names
| Name | (R)-6-(4-Aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one |
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| Synonym | More Synonyms |
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OR-1855 BiologicalActivity
| Description | OR-1855, an active metabolite of Levosimendan, has effect on human myometrial contractility. Levosimendan is a calcium sensitiser used in the management of acutely decompensated congestive heart failure[1][2]. |
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| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>Others |
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| References | [1]. Banfor PN, et al. Comparative effects of levosimendan, OR-1896, OR-1855, dobutamine, and milrinone on vascular resistance, indexes of cardiac function, and O2 consumption in dogs. Am J Physiol Heart Circ Physiol. 2008 Jan;294(1):H238-48. [2]. Mark P. Hehir, et al. 487: OR-1855, a levosimendan metabolite with an effect on human myometrial contractility.December 2009Volume 201, Issue 6, Supplement, Pages S182-S183. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Melting Point | 206-208ºC |
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| Molecular Formula | C11H13N3O |
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| Molecular Weight | 203.240 |
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| Exact Mass | 203.105865 |
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| PSA | 67.48000 |
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| LogP | -0.75 |
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| Index of Refraction | 1.653 |
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| InChIKey | GDMRFHZLKNYRRO-SSDOTTSWSA-N |
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| SMILES | CC1CC(=O)NN=C1c1ccc(N)cc1 |
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| Storage condition | -20?C Freezer |
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2933990090 |
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Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 3(2H)-Pyridazinone, 6-(4-aminophenyl)-4,5-dihydro-5-methyl- |
| 6-(4-Amino-phenyl)-5-methyl-4,5-dih; ydro-2H-pyridazin-3-one |
| (R)-6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone |
| MFCD01692712 |
| 6-(4-Aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one |
| 6-(4-Aminophenyl)-5-methyl-4,5-dihydro-3(2H)-pyridazinone |
| Levosimendan Impurity 6 |
