CAS 123-99-9|Azelaic acid
Introduction：Basic information about CAS 123-99-9|Azelaic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Azelaic acid | ||
|---|---|---|---|
| CAS Number | 123-99-9 | Molecular Weight | 188.221 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 286 ºC (100 mmHg) |
| Molecular Formula | C9H16O4 | Melting Point | 98-103 ºC |
| MSDS | ChineseUSA | Flash Point | 215 ºC |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | azelaic acid |
|---|---|
| Synonym | More Synonyms |
Azelaic acid BiologicalActivity
| Description | Azelaic acid is an organic compound produced by the ozonolysis of oleic acid; component of a number of hair and skin conditioners. |
|---|---|
| Related Catalog | Natural Products >>Acids and AldehydesResearch Areas >>Others |
| Target | Human Endogenous Metabolite |
| References | [1]. Jung HW, et al. Priming in systemic plant immunity. Science. 2009 Apr 3;324(5923):89-91. [2]. Liu RH, et al. Azelaic acid in the treatment of papulopustular rosacea: a systematic review of randomized controlled trials. Arch Dermatol. 2006 Aug;142(8):1047-52. |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 286 ºC (100 mmHg) |
| Melting Point | 98-103 ºC |
| Molecular Formula | C9H16O4 |
| Molecular Weight | 188.221 |
| Flash Point | 215 ºC |
| Exact Mass | 188.104858 |
| PSA | 74.60000 |
| LogP | 1.33 |
| Vapour density | 6.5 (vs air) |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.475 |
| InChIKey | BDJRBEYXGGNYIS-UHFFFAOYSA-N |
| SMILES | O=C(O)CCCCCCCC(=O)O |
| Stability | Stable. Combustible. Incompatible with bases, strong oxidizing agents. Readily biodegrades in soil and water with >70% DOC reduction after 28 days. |
| Water Solubility | 2.4 g/L (20 ºC) |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- EMERY* Emery Industries, Inc., Data Sheets. (4900 Este Ave., Cincinnati, OH 45232) Volume(issue)/page/year: S3B,-,1964
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- EMERY* Emery Industries, Inc., Data Sheets. (4900 Este Ave., Cincinnati, OH 45232) Volume(issue)/page/year: S3B,-,1964 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD-A067-313 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83495 No. of Facilities: 170 (estimated) No. of Industries: 8 No. of Occupations: 11 No. of Employees: 1676 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83495 No. of Facilities: 3427 (estimated) No. of Industries: 35 No. of Occupations: 42 No. of Employees: 34469 (estimated) No. of Female Employees: 7576 (estimated)
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 1 |
| RTECS | CM1980000 |
| HS Code | 2917139000 |
Customs
| HS Code | 2917139000 |
|---|---|
| Summary | 2917139000 azelaic acid, sebacic acid, their salts and esters VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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Synonyms
| Skinoren |
| AZALEIC ACID |
| Azelaate |
| 3,4-Dimethoxybenzaldehyde |
| Nonanedioic acid |
| Azelaic acid |
| UNII-F2VW3D43YT |
| AZELAIC ACID/NONANEDIOIC ACID |
| Barasertib |
| AZELAIC ACID FOR SYNTHESIS |
| INH 34 |
| Azelex |
| Azelaicacid |
| Finaceae |
| lepargylic acid |
| 1,7-HEPTANE DICARBONIC ACID |
| 1,7-HEPTANEDICARBOXYLIC |
| AZD1152-HQPA |
| Azelainic acid |
| HEPTANE-1,7-DICARBOXYLIC ACID |
| Azalaic Acid |
| AZELAIC ACID( MICRONIZED ) |
| EINECS 204-669-1 |
| anchoic acid |
| 1,7-Heptanedicarboxylic acid |
| MFCD00004432 |
