CAS 66635-93-6|(R)-ketorolac

Introduction:Basic information about CAS 66635-93-6|(R)-ketorolac, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name(R)-ketorolac
CAS Number66635-93-6Molecular Weight255.269
Density1.3±0.1 g/cm3Boiling Point493.2±40.0 °C at 760 mmHg
Molecular FormulaC15H13NO3Melting Point163-170°C
MSDS/Flash Point252.1±27.3 °C

Names

Name(R)-ketorolac
SynonymMore Synonyms

(R)-ketorolac BiologicalActivity

Description(R)-Ketorolac is the R-enantiomer of Ketorolac, shows potent analgesic activity, reduces ulcerogenic potential. (R)-Ketorolac is inactive on COX[1].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease
References

[1]. Handley DA, et al. Preclinical enantioselective pharmacology of (R)- and (S)- ketorolac. J Clin Pharmacol. 1998 Feb;38(2S):25S-35S.

Chemical & Physical Properties

Density1.3±0.1 g/cm3
Boiling Point493.2±40.0 °C at 760 mmHg
Melting Point163-170°C
Molecular FormulaC15H13NO3
Molecular Weight255.269
Flash Point252.1±27.3 °C
Exact Mass255.089539
PSA59.30000
LogP2.08
Vapour Pressure0.0±1.3 mmHg at 25°C
Index of Refraction1.659
InChIKeyOZWKMVRBQXNZKK-LLVKDONJSA-N
SMILESO=C(c1ccccc1)c1ccc2n1CCC2C(=O)O
Storage conditionRefrigerator

Synonyms

1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-
Ketorolac
5-(phenylcarbonyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
(R)-Ketorolac
R (+) Ketorolac
UNII:YZI5105V0L
Ketorolac Impurity 1
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