CAS 818-61-1|2-Hydroxyethyl acrylate
Introduction：Basic information about CAS 818-61-1|2-Hydroxyethyl acrylate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Hydroxyethyl acrylate | ||
|---|---|---|---|
| CAS Number | 818-61-1 | Molecular Weight | 116.115 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 196.2±23.0 °C at 760 mmHg |
| Molecular Formula | C5H8O3 | Melting Point | -60 °C |
| MSDS | ChineseUSA | Flash Point | 98.3±0.0 °C |
| Symbol | GHS05, GHS06, GHS09 | Signal Word | Danger |
Names
| Name | 2-Hydroxyethyl acrylate |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 196.2±23.0 °C at 760 mmHg |
| Melting Point | -60 °C |
| Molecular Formula | C5H8O3 |
| Molecular Weight | 116.115 |
| Flash Point | 98.3±0.0 °C |
| Exact Mass | 116.047340 |
| PSA | 46.53000 |
| LogP | -0.05 |
| Vapour density | >1 (vs air) |
| Vapour Pressure | 0.1±0.8 mmHg at 25°C |
| Index of Refraction | 1.440 |
| InChIKey | OMIGHNLMNHATMP-UHFFFAOYSA-N |
| SMILES | C=CC(=O)OCCO |
| Water Solubility | soluble |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 650 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 ppm/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis Behavioral - convulsions or effect on seizure threshold Gastrointestinal - alteration in gastric secretion
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1010 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 38500 ug/m3/9W-I
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Cardiac - EKG changes not diagnostic of specified effects Endocrine - other changes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3900 mg/kg/13W-I
- TOXIC EFFECTS :
- Behavioral - ataxia Nutritional and Gross Metabolic - weight loss or decreased weight gain Nutritional and Gross Metabolic - body temperature decrease
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 38500 ug/m3/9W-I
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Cardiac - EKG changes not diagnostic of specified effects Related to Chronic Data - death
MUTATION DATA - TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Rodent - mouse Lymphocyte
- DOSE/DURATION :
- 15 mg/L
- REFERENCE :
- MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 4,381,1989 *** REVIEWS *** TOXICOLOGY REVIEW EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 11,141,1975 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1326 No. of Facilities: 63 (estimated) No. of Industries: 1 No. of Occupations: 6 No. of Employees: 1845 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1326 No. of Facilities: 107 (estimated) No. of Industries: 4 No. of Occupations: 11 No. of Employees: 2370 (estimated) No. of Female Employees: 354 (estimated)
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Rodent - mouse Lymphocyte
- DOSE/DURATION :
- 15 mg/L
- REFERENCE :
- MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 4,381,1989 *** REVIEWS *** TOXICOLOGY REVIEW EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 11,141,1975 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1326 No. of Facilities: 63 (estimated) No. of Industries: 1 No. of Occupations: 6 No. of Employees: 1845 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1326 No. of Facilities: 107 (estimated) No. of Industries: 4 No. of Occupations: 11 No. of Employees: 2370 (estimated) No. of Female Employees: 354 (estimated)
Safety Information
| Symbol | GHS05, GHS06, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H311-H314-H317-H400 |
| Precautionary Statements | P273-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338-P333 + P313 |
| Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | T:Toxic;N:Dangerousfortheenvironment; |
| Risk Phrases | R20/22;R24;R34;R43;R50 |
| Safety Phrases | S26-S36/39-S45-S61-S36/37/39 |
| RIDADR | UN 2927 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | AT1750000 |
| Packaging Group | II |
| Hazard Class | 8 |
| HS Code | 2916129000 |
Customs
| HS Code | 2916129000 |
|---|---|
| Summary | 2916129000 other esters of acrylic acid VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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Synonyms
| 2-Propenoic acid, 2-hydroxyethyl ester |
| bisomer2hea |
| 2-Hydroxyethyl acryl |
| Hydroxyethyl acrylate |
| HEA |
| ethylene glycol monoacrylate |
| methanol,methyl acrylate |
| 2-hydroxyethyl prop-2-enoate |
| acrylic acid 2-hydroxy-ethyl ester |
| 4-acryloyloxyethyl alcohol |
| EINECS 212-454-9 |
| 2-Hydroxyethylacrylat |
| MFCD00002865 |
| 2-Hydroxyethyl acrylate |
| Glycolmonoacrylate |
