Introduction：Basic information about CAS 62265-68-3|Quinfamide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Quinfamide |
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| CAS Number | 62265-68-3 | Molecular Weight | 354.18 |
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| Density | 1.428g/cm3 | Boiling Point | 551.3ºC at 760mmHg |
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| Molecular Formula | C16H13Cl2NO4 | Melting Point | 145-146ºC |
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| MSDS | / | Flash Point | 287.2ºC |
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Names
| Name | [1-(2,2-dichloroacetyl)-3,4-dihydro-2H-quinolin-6-yl] furan-2-carboxylate |
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| Synonym | More Synonyms |
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Quinfamide BiologicalActivity
| Description | Quinfamide is an antiamebic agent. Quinfamide can be used to treat tropical parasitic infections such as Amoebiasis and Helminthiasis[1]. |
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| Related Catalog | Signaling Pathways >>Anti-infection >>ParasiteResearch Areas >>Infection |
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| References | [1]. Davila-Gutierrez CE, et al. Nitazoxanide compared with quinfamide and mebendazole in the treatment of helminthic infections and intestinal protozoa in children. Am J Trop Med Hyg. 2002 Mar;66(3):251-4. |
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Chemical & Physical Properties
| Density | 1.428g/cm3 |
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| Boiling Point | 551.3ºC at 760mmHg |
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| Melting Point | 145-146ºC |
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| Molecular Formula | C16H13Cl2NO4 |
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| Molecular Weight | 354.18 |
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| Flash Point | 287.2ºC |
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| Exact Mass | 353.02200 |
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| PSA | 59.75000 |
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| LogP | 3.64670 |
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| Index of Refraction | 1.599 |
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| InChIKey | SBJGFIXQRZOVTO-UHFFFAOYSA-N |
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| SMILES | O=C(Oc1ccc2c(c1)CCCN2C(=O)C(Cl)Cl)c1ccco1 |
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| Storage condition | 2-8°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- LU0215000
- CHEMICAL NAME :
- 2-Furancarboxylic acid, 1-(dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl ester
- CAS REGISTRY NUMBER :
- 62265-68-3
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C16-H13-Cl2-N-O4
- MOLECULAR WEIGHT :
- 354.20
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 22,599,1979
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - hamster
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 22,599,1979
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Safety Information
Customs
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 1-(dichloroacetyl)-1,2,3,4-tetrahydroquinolin-6-yl 2-furoate |
| Quinfamido [INN-Spanish] |
| Quinfamide |
| Quinfamidum [INN-Latin] |
| 1-(dichloroacetyl)-6-(2-furoyloxy)-1,2,3,4-tetrahydroquinoline |
| EINECS 263-478-1 |
| Amenide |
