Introduction：Basic information about CAS 4871-40-3|MAC13772, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | MAC13772 |
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| CAS Number | 4871-40-3 | Molecular Weight | 227.24000 |
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| Density | 1.44 g/cm3 | Boiling Point | 461ºC at 760mmHg |
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| Molecular Formula | C8H9N3O3S | Melting Point | / |
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| MSDS | / | Flash Point | 232.6ºC |
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Names
| Name | 2-(2-nitrophenyl)sulfanylacetohydrazide |
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| Synonym | More Synonyms |
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MAC13772 BiologicalActivity
| Description | MAC13772 is a potent inhibitor of the enzyme BioA (IC50=250 nM), the antepenultimate step in biotin biosynthesis. MAC13772 is a novel antibacterial compound[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| Target | IC50: 250 nM (BioA)[1] |
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| References | [1]. Zlitni S, et al. Metabolic suppression identifies new antibacterial inhibitors under nutrient limitation. Nat Chem Biol. 2013 Dec;9(12):796-804. |
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Chemical & Physical Properties
| Density | 1.44 g/cm3 |
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| Boiling Point | 461ºC at 760mmHg |
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| Molecular Formula | C8H9N3O3S |
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| Molecular Weight | 227.24000 |
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| Flash Point | 232.6ºC |
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| Exact Mass | 227.03600 |
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| PSA | 126.24000 |
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| LogP | 2.29120 |
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| Index of Refraction | 1.649 |
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| InChIKey | CZXFCCXLFQCYBK-UHFFFAOYSA-N |
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| SMILES | NNC(=O)CSc1ccccc1[N+](=O)[O-] |
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Synonyms
| 2-[(2-Nitrophenyl)thio]acetic Acid Hydrazide |
| 2-(2-Nitro-phenylmercapto)-essigsaeure-hydrazid |
| 2-(2-nitrophenylthio)acetohydrazide |
| 2-[(2-nitrophenyl)thio]ethanohydrazide |
