CAS 3731-51-9|2-Picolylamine

Introduction：Basic information about CAS 3731-51-9|2-Picolylamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles18
7. Synonyms

Common Name	2-Picolylamine
CAS Number	3731-51-9	Molecular Weight	108.141
Density	1.1±0.1 g/cm3	Boiling Point	203.0±0.0 °C at 760 mmHg
Molecular Formula	C₆H₈N₂	Melting Point	20°C
MSDS	ChineseUSA	Flash Point	90.0±0.0 °C
Symbol	GHS05	Signal Word	Danger

Names

Name	2-Picolylamine
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	203.0±0.0 °C at 760 mmHg
Melting Point	20°C
Molecular Formula	C₆H₈N₂
Molecular Weight	108.141
Flash Point	90.0±0.0 °C
Exact Mass	108.068748
PSA	24.92000
LogP	-0.40
Vapour Pressure	0.3±0.4 mmHg at 25°C
Index of Refraction	1.552
InChIKey	WOXFMYVTSLAQMO-UHFFFAOYSA-N
SMILES	NCc1ccccn1
Water Solubility	SOLUBLE

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: US1840000

CHEMICAL NAME :: Pyridine, 2-aminomethyl-

CAS REGISTRY NUMBER :: 3731-51-9

BEILSTEIN REFERENCE NO. :: 0108054

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C6-H8-N2

MOLECULAR WEIGHT :: 108.16

WISWESSER LINE NOTATION :: T6NJ B1Z

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 340 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 26,345,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: 750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 12,355,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - wild bird species

DOSE/DURATION :: 562 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 12,355,1983

Safety Information

Symbol	GHS05
Signal Word	Danger
Hazard Statements	H314
Precautionary Statements	P280-P305 + P351 + P338-P310
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	C:Corrosive;
Risk Phrases	R34
Safety Phrases	S26-S36/37/39-S45-S25
RIDADR	UN 2735 8/PG 2
WGK Germany	3
RTECS	US1840000
Packaging Group	III
Hazard Class	8
HS Code	29333999

Customs

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles18

Carbonic anhydrase activators: activation of the human tumor-associated isozymes IX and XII with amino acids and amines.

Bioorg. Med. Chem. 16 , 3530-6, (2008)

The first activation study of the human carbonic anhydrase (hCA, EC 4.2.1.1) isoforms associated to tumors, hCA IX and XII, with a small library of natural and non-natural amino acids as well as aroma...

Carbonic anhydrase activators: activation of isozyme XIII with amino acids and amines.

Bioorg. Med. Chem. Lett. 16 , 3955-9, (2006)

The first activation study of isoform XIII of carbonic anhydrase (CA, EC 4.2.1.1) is reported. A series of amino acids and amines incorporating protonatable moieties of the primary/heterocyclic amine ...

Carbonic anhydrase activators: the first activation study of the human secretory isoform VI with amino acids and amines.

Bioorg. Med. Chem. 15 , 5351-7, (2007)

The secretory isozyme of human carbonic anhydrase (hCA, EC 4.2.1.1), hCA VI, has been cloned, expressed, and purified in a bacterial expression system. The kinetic parameters for the CO(2) hydration r...

Synonyms

aminomethylpyridine

2-Methyl-3-pyridinamine

2-Pyridinemethanamine

MFCD00129044

3-Amino-2-picoline

3-Pyridinamine, 2-methyl-

1-(pyridin-2-yl)methanamine

2-Picolylamine

2-(Aminomethyl)pyridine

Pyridine, 2-(aminomethyl)-

EINECS 223-090-5

2-Methylpyridin-3-amin

1-(2-Pyridinyl)methanamine

2-(Aminomethyl)pyridine;2-picolylamine

Pyridine, 2- (aminomethyl)-

N-2-Pyridylmethylamine

2-picolinamine

pyridin-2-ylmethanamine

2-aminomethyl-pyridine

2-methylpyridin-3-amine

2-Aminomethylpyridine

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