CAS 505-66-8|Homopiperazine

Introduction：Basic information about CAS 505-66-8|Homopiperazine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles1
7. Synonyms

Common Name	Homopiperazine
CAS Number	505-66-8	Molecular Weight	100.162
Density	0.9±0.1 g/cm3	Boiling Point	169.0±8.0 °C at 760 mmHg
Molecular Formula	C₅H₁₂N₂	Melting Point	38-40 °C(lit.)
MSDS	ChineseUSA	Flash Point	64.4±0.0 °C
Symbol	GHS05, GHS06	Signal Word	Danger

Names

Name	Homopiperazine
Synonym	More Synonyms

Chemical & Physical Properties

Density	0.9±0.1 g/cm3
Boiling Point	169.0±8.0 °C at 760 mmHg
Melting Point	38-40 °C(lit.)
Molecular Formula	C₅H₁₂N₂
Molecular Weight	100.162
Flash Point	64.4±0.0 °C
Exact Mass	100.100044
PSA	24.06000
LogP	-0.48
Vapour Pressure	1.6±0.3 mmHg at 25°C
Index of Refraction	1.425
InChIKey	FQUYSHZXSKYCSY-UHFFFAOYSA-N
SMILES	C1CNCCNC1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HM3850000

CHEMICAL NAME :: 1H-1,4-Diazepine, hexahydro-

CAS REGISTRY NUMBER :: 505-66-8

BEILSTEIN REFERENCE NO. :: 0102711

LAST UPDATED :: 199709

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C5-H12-N2

MOLECULAR WEIGHT :: 100.19

WISWESSER LINE NOTATION :: T7M DMTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,882,1986

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,882,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2830 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1050 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

Safety Information

Symbol	GHS05, GHS06
Signal Word	Danger
Hazard Statements	H311-H314
Precautionary Statements	P280-P305 + P351 + P338-P310
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	C:Corrosive
Risk Phrases	R21;R34
Safety Phrases	S26-S36/37/39-S45
RIDADR	UN 3259 8/PG 2
WGK Germany	1
RTECS	HM3850000
Packaging Group	III
Hazard Class	8
HS Code	2942000000

Customs

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles1

Orthovanadate-Induced Vasoconstriction of Rat Mesenteric Arteries Is Mediated by Rho Kinase-Dependent Inhibition of Myosin Light Chain Phosphatase.

Biol. Pharm. Bull. 38 , 1809-16, (2015)

Orthovanadate (OVA), a protein tyrosine phosphatase inhibitor, induces vasoconstriction in a Rho kinase-dependent manner. The aim of this study was to determine the mechanism underlying OVA-induced va...

Synonyms

hexahydro-1H-1,4-diazepine

EINECS 208-016-1

1,4-diazacycloheptane

1,4-Diazacycloheptane,2,3,4,5,6,7-Hexahydro-1H-1,4-diazepine

High-piperazine

hexahydro-4H-1,4-diazepine

hexahydro-1,4-diazepine

1,4-Diazepane

Homopiperazine

HOJNEYSUCKLEEXTRACT

HPRZ

1H-1,4-Diazepine, hexahydro-

Homo-Piperazines

MFCD00006933

tetrahydro-1,4-diazepine

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