CAS 7681-67-6|Propionylpromazine hydrochloride
Introduction：Basic information about CAS 7681-67-6|Propionylpromazine hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Propionylpromazine hydrochloride | ||
|---|---|---|---|
| CAS Number | 7681-67-6 | Molecular Weight | 376.94300 |
| Density | / | Boiling Point | 507.4ºC at 760 mmHg |
| Molecular Formula | C20H25ClN2OS | Melting Point | 90-93ºC |
| MSDS | USA | Flash Point | 260.7ºC |
Names
| Name | 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]propan-1-one,hydrochloride |
|---|---|
| Synonym | More Synonyms |
Propionylpromazine hydrochloride BiologicalActivity
| Description | Propionylpromazine hydrochloride (Propiopromazine hydrochloride), a dopamine receptor D2 (DRD2) antagonist, can be used in the research of Parkinson disease[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Dopamine ReceptorSignaling Pathways >>Neuronal Signaling >>Dopamine ReceptorResearch Areas >>Neurological Disease |
| Target | D2 Receptor |
| References | [1]. Tyers, Mike, et al. Method for treating a brain cancer with ifenprodil. US8058243. |
Chemical & Physical Properties
| Boiling Point | 507.4ºC at 760 mmHg |
|---|---|
| Melting Point | 90-93ºC |
| Molecular Formula | C20H25ClN2OS |
| Molecular Weight | 376.94300 |
| Flash Point | 260.7ºC |
| Exact Mass | 376.13800 |
| PSA | 48.85000 |
| LogP | 5.70070 |
| InChIKey | ZFWVWZODBGTOIL-UHFFFAOYSA-N |
| SMILES | CCC(=O)c1ccc2c(c1)N(CCCN(C)C)c1ccccc1S2.Cl |
| Storage condition | 2-8°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S22 |
| RIDADR | UN 2811 |
| WGK Germany | 3 |
Articles20
More Articles| Chemical genetics reveals a complex functional ground state of neural stem cells. Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc... | |
| Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nat. Chem. Biol. 5 , 765-71, (2009) Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened... | |
| [Electrocardiography alterations in horses caused by preanesthetic medication with combelen]. Berl. Munch. Tierarztl. Wochenschr. 93(9) , 163-6, (1980) |
Synonyms
| PROPIOPROMAZINE HYDROCHLORIDE |
| Propionylpromazine hydrochloride |
