Introduction：Basic information about CAS 141743-15-9|Fmoc-N-(2-Boc-aminoethyl)-Gly-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Fmoc-N-(2-Boc-aminoethyl)-Gly-OH |
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| CAS Number | 141743-15-9 | Molecular Weight | 440.48900 |
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| Density | 1.25 g/cm3 | Boiling Point | 638.3ºC at 760 mmHg |
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| Molecular Formula | C24H28N2O6 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | 339.8ºC |
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| Symbol |
GHS09 | Signal Word | Warning |
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Names
| Name | 2-[9H-fluoren-9-ylmethoxycarbonyl-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethyl]amino]acetic acid |
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| Synonym | More Synonyms |
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Fmoc-N-(2-Boc-aminoethyl)-Gly-OH BiologicalActivity
| Description | Fmoc-N-(2-Boc-aminoethyl)-Gly-OH is a Fmoc-protected glycine derivative that can be used in antibody drug coupling (ADC) synthesis. ADC consists of antibodies that are linked to ADC cytotoxins via ADC junctions[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker |
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| References | [1]. Hiroyuki Naito, et al. (anti-her2 antibody)-drug conjugate. EP3130608 |
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Chemical & Physical Properties
| Density | 1.25 g/cm3 |
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| Boiling Point | 638.3ºC at 760 mmHg |
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| Molecular Formula | C24H28N2O6 |
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| Molecular Weight | 440.48900 |
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| Flash Point | 339.8ºC |
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| Exact Mass | 440.19500 |
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| PSA | 105.17000 |
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| LogP | 4.23770 |
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| InChIKey | SMLJSDLXJRGOKW-UHFFFAOYSA-N |
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| SMILES | CC(C)(C)OC(=O)NCCN(CC(=O)O)C(=O)OCC1c2ccccc2-c2ccccc21 |
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Safety Information
| Symbol |
GHS09 |
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| Signal Word | Warning |
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| Hazard Statements | H410 |
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| Precautionary Statements | P273-P501 |
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| Personal Protective Equipment | Eyeshields;Gloves |
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| Risk Phrases | R50/53 |
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| Safety Phrases | 60-61 |
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| RIDADR | UN 3077 9/PG 3 |
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Synonyms
| N-[2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]Ethyl]-N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-Glycine |
| Fmoc-N-(2-Boc-aminoethyl)glycine |
| N-(2-tert-Butoxycarbonylaminoethyl)-N-(9-fluorenylmethoxycarbonyl)aminoacetic acid |
| AmbotzFAA1767 |
| N-<2-(N-Boc)aminoethyl>-N-<Fmoc>glycine |
| Boc-Aeg(Fmoc)-OH |
| N'-Boc-N-Fmoc-aminoethylglycine |
| N-[tert-butyloxycarbonyl]-[N'-fluorenylmethyloxycarbonyl-(2'-aminoethyl)]glycine |
| FMOC-N-(N'-BOC-2-aminoethyl)glycine |
| Fmoc-N-(2-Boc-aminoethyl)-Gly-OH |
| N-[2-(tert-Butyloxycarbonylamino)ethyl]-N-fluorenylmethyloxycarbonylglycine |
