Introduction：Basic information about CAS 524-81-2|Mebhydrolin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Mebhydrolin |
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| CAS Number | 524-81-2 | Molecular Weight | 276.37600 |
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| Density | 1.12 g/cm3 | Boiling Point | 856.1ºC at 760 mmHg |
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| Molecular Formula | C19H20N2 | Melting Point | / |
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| MSDS | / | Flash Point | 471.6ºC |
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Names
| Name | 5-benzyl-2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indole |
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| Synonym | More Synonyms |
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Mebhydrolin BiologicalActivity
| Description | Mebhydrolin is a specific histamine H1 receptor antagonist. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Histamine ReceptorSignaling Pathways >>Immunology/Inflammation >>Histamine ReceptorResearch Areas >>Inflammation/Immunology |
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| Target | Histamine H1-receptor[1] |
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| In Vitro | Mebhydrolin is a specific histamine H1-receptor antagonist with minimal sedative properties and comparing it with the effects of chlorpromazine, the archetypical phenothiazine[1]. Mebhydrolin exerts an antihistaminic effect over the period of the ethanol interaction study[2]. |
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| References | [1]. O'Neill PA, et al. Chlorpromazine-a specific effect on breathlessness? Br J Clin Pharmacol. 1985 Jun;19(6):793-7. [2]. Franks HM, et al. Interaction between ethanol and antihistamines: 3. Mebhydrolin. Med J Aust. 1981 Oct 31;2(9):477-9. |
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Chemical & Physical Properties
| Density | 1.12 g/cm3 |
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| Boiling Point | 856.1ºC at 760 mmHg |
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| Molecular Formula | C19H20N2 |
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| Molecular Weight | 276.37600 |
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| Flash Point | 471.6ºC |
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| Exact Mass | 276.16300 |
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| PSA | 8.17000 |
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| LogP | 3.61540 |
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| Index of Refraction | 1.633 |
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| InChIKey | FQQIIPAOSKSOJM-UHFFFAOYSA-N |
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| SMILES | CN1CCc2c(c3ccccc3n2Cc2ccccc2)C1 |
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| Storage condition | 2-8℃ |
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Synonyms
| Mebhydrolin |
| 5-Benzyl-2,3,4,5-tetrahydro-2-methyl-1H-pyrido[4,3-b]indol |
| Mebhydrolinum [INN-Latin] |
| Mebhydroline |
| 5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole |
| 5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol |
| 9-benzyl-3-methyl-1,2,3,4-tetrahydro-3-carboline |
| 3-methyl-9-benzyl-1,2,3,4-tetrahydrocarboline |
| Mebhydroline [INN-French] |
| Mebhidrolina [INN-Spanish] |
| EINECS 208-364-4 |
