Introduction：Basic information about CAS 52365-63-6|Dipivefrin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Dipivefrin |
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| CAS Number | 52365-63-6 | Molecular Weight | 351.43700 |
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| Density | 1.097 g/cm3 | Boiling Point | 473.7ºC at 760 mmHg |
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| Molecular Formula | C19H29NO5 | Melting Point | 146-147° |
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| MSDS | / | Flash Point | 240.3ºC |
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Names
| Name | dipivefrin |
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| Synonym | More Synonyms |
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Dipivefrin BiologicalActivity
| Description | Dipivefrin is a potent adrenergic agonist. Dipivefrin is an adrenergic pro-drug. Dipivefrin can be used for reduce IOP (intraocular pressure) in patients suffering from chronic open angle glaucoma[1][2]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>GPCR/G Protein >>Adrenergic Receptor |
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| Target | Human Endogenous Metabolite |
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| References | [1]. Kass MA,et al. Dipivefrin and epinephrine treatment of elevated intraocular pressure: a comparative study. Arch Ophthalmol. 1979 Oct;97(10):1865-6. [2]. Alkholief M, et al. Thermoresponsive sol-gel improves ocular bioavailability of Dipivefrin hydrochloride and potentially reduces the elevated intraocular pressure in vivo. Saudi Pharm J. 2020 Aug;28(8):1019-1029. |
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Chemical & Physical Properties
| Density | 1.097 g/cm3 |
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| Boiling Point | 473.7ºC at 760 mmHg |
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| Melting Point | 146-147° |
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| Molecular Formula | C19H29NO5 |
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| Molecular Weight | 351.43700 |
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| Flash Point | 240.3ºC |
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| Exact Mass | 351.20500 |
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| PSA | 84.86000 |
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| LogP | 3.23330 |
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| Index of Refraction | 1.511 |
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| InChIKey | OCUJLLGVOUDECM-UHFFFAOYSA-N |
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| SMILES | CNCC(O)c1ccc(OC(=O)C(C)(C)C)c(OC(=O)C(C)(C)C)c1 |
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Safety Information
Customs
| HS Code | 2922509090 |
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| Summary | 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| Dipivefrina |
| [2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate |
| AKPro |
| Dipivefrine |
| Dipivefrinum |
| Dipivefrina [INN-Spanish] |
| Dipivefrinum [INN-Latin] |
| Dipivefrin [USAN] |
| dipivalyl epinephrine |
| Propine |
