CAS 109909-44-6|Deoxycytidine triphosphate trisodium salt

Introduction：Basic information about CAS 109909-44-6|Deoxycytidine triphosphate trisodium salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Deoxycytidine triphosphate trisodium salt
CAS Number	109909-44-6	Molecular Weight	533.102
Density	/	Boiling Point	/
Molecular Formula	C₉H₁₃N₃Na₃O₁₃P₃	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	2'-deoxycytidine-5'-triphosphate trisodium salt
Synonym	More Synonyms

BiologicalActivity

Description	Deoxycytidine triphosphate trisodium salt (dCTP trisodium salt) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing[1][2][3].
Related Catalog	Signaling Pathways >>Cell Cycle/DNA Damage >>DNA/RNA SynthesisSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Metabolic Disease
In Vitro	Assays of thirteen cell lines, derived from mouse lymphomas, myelomas, myeloid tumors, and a mastocytoma, for sensitivity to growth inhibition by 1-β-D-arabinofuranosylcytosine (ara-C) revealed a spectrum between the most and least sensitive which differed 100-fold from each other. An inverse correlation between sensitivity and cellular Deoxycytidine triphosphate (2′-Deoxycytidine-5′-triphosphate, dCTP) content is found, and this suggested that sensitivity of cells might be increased if the dCTP content was lowered during cell exposure to ara-C[1]. Deoxycytidine triphosphate trisodium salt is a phosphoethanolamine cytidylyltransferase substrate[2].
References	[1]. A W Harris, et al. Effect of thymidine on the sensitivity of cultured mouse tumor cells to 1-beta-D-arabinofuranosylcytosine. Cancer Res. 1979 Feb;39(2 Pt 1):538-41. [2]. B A Bladergroen, et al. CTP:phosphoethanolamine cytidylyltransferase. Biochim Biophys Acta. 1997 Sep 4;1348(1-2):91-9. [3]. M H Tattersall, et al. Deoxyribonucleoside triphosphates in human cells: changes in disease and following exposure to drugs. Eur J Clin Invest. 1975 Apr;5(2):191-202.

Chemical & Physical Properties

Molecular Formula	C₉H₁₃N₃Na₃O₁₃P₃
Molecular Weight	533.102
Exact Mass	532.935425
PSA	288.11000
LogP	0.71300
InChIKey	WBIPTAOOMJEGQO-MILVPLDLSA-K
SMILES	Nc1ccn(C2CC(O)C(COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])O)O2)c(=O)n1.[Na+].[Na+].[Na+]
Storage condition	2-8℃

Synonyms

((2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyltriphosphoric acid,trisodium salt

2'-DEOXYCYTIDINE-5'-TRIPHOSPHORIC ACID TRISODIUM SALT

Dctp-Na3

CYTIDINE 5''-(TETRAHYDROGEN TRIPHOSPHATE),2''-DEOXY-,TRISODIUM SALT

Trisodium 2'-deoxy-5'-O-[({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphinato]cytidine

Deoxycytidine-5'-Triphosphoric Acid Trisodium Sal

Cytidine, 2'-deoxy-, 5'-(tetrahydrogen triphosphate), sodium salt (1:3)

DCTP (SODIUM SALT)

2'-DEOXYCYTIDINE 5'-TRIPHOSPHATE (SODIUM SALT)

MFCD00080336

dCTP,3Na

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