Introduction：Basic information about CAS 106375-28-4|ω-Conotoxin GVIA trifluoroacetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | ω-Conotoxin GVIA trifluoroacetate salt |
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| CAS Number | 106375-28-4 | Molecular Weight | 3037.35000 |
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| Density | 1.71 | Boiling Point | / |
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| Molecular Formula | C120H182N38O43S6 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | / |
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Names
| Name | ω-Conotoxin GVIA |
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| Synonym | More Synonyms |
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ω-Conotoxin GVIA trifluoroacetate salt BiologicalActivity
| Description | ω-Conotoxin GVIA is an inhibitor of the N-type Ca2+ channel[1]. |
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| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>Calcium ChannelResearch Areas >>Neurological Disease |
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| In Vitro | ω-conotoxin GVIA (50 nM, 50 nL) inhibits the effects of urotensin II (UII)[1]. |
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| References | [1]. Ya-Kun Cao, et al. Microinjection of urotensin II into the rostral ventrolateral medulla increases sympathetic vasomotor tone via the GPR14/ERK pathway in rats. Hypertens Res. 2020 Aug;43(8):765-771. |
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Chemical & Physical Properties
| Density | 1.71 |
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| Molecular Formula | C120H182N38O43S6 |
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| Molecular Weight | 3037.35000 |
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| Exact Mass | 3035.15000 |
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| PSA | 1496.38000 |
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| InChIKey | FDQZTPPHJRQRQQ-UHFFFAOYSA-N |
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| SMILES | CC(O)C1NC(=O)C(Cc2ccc(O)cc2)NC(=O)C2CC(O)CN2C(=O)C(CC(N)=O)NC(=O)C2CSSCC3NC(=O)C(CO)NC(=O)C(CO)NC(=O)CNC(=O)C4CC(O)CN4C(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C(N)CSSCC(NC(=O)C(CSSCC(C(=O)NC(Cc4ccc(O)cc4)C(N)=O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCCN)NC1=O)NC(=O)C(CC(N)=O)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CC(O)CN1C(=O)C(CO)NC3=O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CO)C(=O)N2 |
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| Storage condition | −20°C |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | UN 3172 |
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| WGK Germany | 3 |
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| RTECS | GL2665050 |
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| Packaging Group | III |
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| Hazard Class | 6.1(b) |
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Articles2
More Articles
| Differential blockade of rat alpha3beta4 and alpha7 neuronal nicotinic receptors by omega-conotoxin MVIIC, omega-conotoxin GVIA and diltiazem. Br. J. Pharmacol. 127 , 1375, (1999) Rat alpha3beta4 or alpha7 neuronal nicotinic acetylcholine receptors (AChRs) were expressed in Xenopus laevis oocytes, and the effects of various toxins and non-toxin Ca2+ channel blockers studied. Ni... | |
| Spermine does not compete with omega-conotoxin GVIA in the striatum radiatum of the hippocampal slice. Brain Res. 772 , 191, (1997) The effect of spermine (Spm) and of omega-conotoxin GVIA (CTX) on the population excitatory postsynaptic potentials (pEPSP) in stratum radiatum of the CA1 area were compared. CTX decreased irreversibl... | |
Synonyms
| w-ConotoxinGVIA |
| w-Conotoxin GVIA,Conus geographus |
| o-Conotoxin GVIA |
| MFCD00076620 |
| M.W. 3037.35 C120H182N38O43S6 |
