CAS 593-84-0|Guanidine thiocyanate
| Common Name | Guanidine thiocyanate | ||
|---|---|---|---|
| CAS Number | 593-84-0 | Molecular Weight | 118.16 |
| Density | 1.103 g/mL at 20 °C | Boiling Point | 132.9ºC at 760 mmHg |
| Molecular Formula | C2H6N4S | Melting Point | 120-122 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 34.2ºC |
| Symbol | GHS05, GHS07 | Signal Word | Danger |
Names
| Name | Guanidine thiocyanate |
|---|---|
| Synonym | More Synonyms |
Guanidine thiocyanate BiologicalActivity
| Description | Guanidine thiocyanate is a chaotropic agent. Guanidine thiocyanate can be used as a protein denaturant and a nucleic acid protector in the extraction of DNA and RNA from cells[1]. |
|---|---|
| Related Catalog | Research Areas >>Others |
| Target | Human Endogenous Metabolite |
| References | [1]. Mason PE, et al. The hydration structure of guanidinium and thiocyanate ions: implications for protein stability in aqueous solution. Proc Natl Acad Sci U S A. 2003;100(8):4557-4561. |
Chemical & Physical Properties
| Density | 1.103 g/mL at 20 °C |
|---|---|
| Boiling Point | 132.9ºC at 760 mmHg |
| Melting Point | 120-122 °C(lit.) |
| Molecular Formula | C2H6N4S |
| Molecular Weight | 118.16 |
| Flash Point | 34.2ºC |
| Exact Mass | 118.031319 |
| PSA | 138.48000 |
| LogP | 0.73618 |
| Index of Refraction | n20/D 1.482 |
| InChIKey | ZJYYHGLJYGJLLN-UHFFFAOYSA-N |
| SMILES | N#CS.N=C(N)N |
| Storage condition | Store at RT. |
| Stability | Stability Stable, but light sensitive. Incompatible with acids (contact releases very toxic gas), strong oxidising agents. |
| Water Solubility | H2O: 6 M at 20 °C, clear, colorless |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
Safety Information
| Symbol | GHS05, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302 + H312 + H332-H314-H412 |
| Supplemental HS | Contact with acids liberates very toxic gas. |
| Precautionary Statements | P273-P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R20/21/22;R32;R52/53 |
| Safety Phrases | S36/37-S61-S13 |
| RIDADR | 1759 |
| WGK Germany | 2 |
| RTECS | XL1225000 |
| Packaging Group | III |
| Hazard Class | 8 |
| HS Code | 2925290090 |
Customs
| HS Code | 2925290090 |
|---|---|
| Summary | 2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
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Synonyms
| GUANIDINE RHODANIDE |
| Guanidine, thiocyanate (1:1) |
| Guandine thiocyanate |
| thiocyanic acid,guanidine salt |
| Guanidinethiocyanate |
| GUANIDINIUM RHODANIDE |
| MFCD00013027 |
| Guanidine isothiocyanate |
| Guanidine thiocyanate |
| Guanidine thiocyanate (1:1) |
| Guanidine thiocyanat |
| Guanidinium thiocyanate |
| GdmSCN |
| guanidine monothiocyanate |
| usafek-705 |
| GTC |
| Guanidiniumthiocyanat |
| EINECS 209-812-1 |
