CAS 50539-45-2|1-(4-anilinonaphthalen-1-yl)pyrrole-2,5-dione

Introduction：Basic information about CAS 50539-45-2|1-(4-anilinonaphthalen-1-yl)pyrrole-2,5-dione, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name1-(4-anilinonaphthalen-1-yl)pyrrole-2,5-dione
CAS Number50539-45-2Molecular Weight314.33700
Density1.364g/cm3Boiling Point521.6ºC at 760 mmHg
Molecular FormulaC20H14N2O2Melting Point207ºC
MSDS/Flash Point269.3ºC

Names

Name1-(4-anilinonaphthalen-1-yl)pyrrole-2,5-dione
SynonymMore Synonyms

BiologicalActivity

DescriptionN-(4-Anilino-1-naphthyl)maleimide is a fluorescent probe that can be used to detect thiol groups in proteins. N-(4-Anilino-1-naphthyl)maleimide reacts with thiol groups and immediately produces a stable fluorescent compound with the λex=355 nm, λem=448 nm[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
In VitroN-(4-Anilino-1-naphthyl)maleimide can be used to label rabbit muscle fibers and its fluorescence spectrum reflects their conformational changes between relaxed or contracted states[2].
References

[1]. T Honda, et al. Characterization of the reactivity of sulphydryl groups in tryptophanase by a dual-monitoring high-performance liquid chromatographic system with a site-directed fluorescent reagent. J Chromatogr. 1986 Dec 26;371:353-60.

[2]. S Chaen, et al. Fluorescence properties and contraction characteristics of ANM (N-(1-anilinonaphthyl-4)maleimide)-labeled rabbit psoas muscle fibers. J Biochem. 1985 Oct;98(4):939-47.

Chemical & Physical Properties

Density1.364g/cm3
Boiling Point521.6ºC at 760 mmHg
Melting Point207ºC
Molecular FormulaC20H14N2O2
Molecular Weight314.33700
Flash Point269.3ºC
Exact Mass314.10600
PSA49.41000
LogP4.15080
Index of Refraction1.746
InChIKeyDUFUXAHBRPMOFG-UHFFFAOYSA-N
SMILESO=C1C=CC(=O)N1c1ccc(Nc2ccccc2)c2ccccc12

Safety Information

Hazard CodesXi
Risk Phrases36/37/38
Safety Phrases26-36
HS Code2925190090

Customs

HS Code2925190090
Summary2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Synonyms

MFCD00042694
EINECS 256-618-8
N-Maleimido-N`-phenyl-1,4-Naphthalenediamine
CAS 876316-26-6|4-(3-METHYL-1,2,4-OXADIAZOL-5-YL)BENZOYL CHLORIDE 97+
CAS 51012-91-0|N-(7-γ-glutamyl)-α-naphthylamide,N-(γ-L-GLUTAMYL)-1-NAPHTHYLAMIDE
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