Introduction：Basic information about CAS 17680-99-8|P-TOLYL-BETA-D-GLUCURONIDE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | P-TOLYL-BETA-D-GLUCURONIDE |
|---|
| CAS Number | 17680-99-8 | Molecular Weight | 284.26200 |
|---|
| Density | 1.524g/cm3 | Boiling Point | 549.7ºC at 760mmHg |
|---|
| Molecular Formula | C13H16O7 | Melting Point | / |
|---|
| MSDS | USA | Flash Point | 211.6ºC |
|---|
Names
| Name | (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(4-methylphenoxy)oxane-2-carboxylic acid |
|---|
| Synonym | More Synonyms |
|---|
P-TOLYL-BETA-D-GLUCURONIDE BiologicalActivity
| Description | p-Cresol glucuronide, a metabolite of p-cresol, is a prototype protein-bound uremic toxin. p-Cresol glucuronide is associated with chronic kidney disease (CKD)[1]. |
|---|
| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>Others |
|---|
| References | [1]. Liabeuf S, et al. Does p-cresylglucuronide have the same impact on mortality as other protein-bound uremic toxins? PLoS One. 2013 Jun 24;8(6):e67168. |
|---|
Chemical & Physical Properties
| Density | 1.524g/cm3 |
|---|
| Boiling Point | 549.7ºC at 760mmHg |
|---|
| Molecular Formula | C13H16O7 |
|---|
| Molecular Weight | 284.26200 |
|---|
| Flash Point | 211.6ºC |
|---|
| Exact Mass | 284.09000 |
|---|
| PSA | 116.45000 |
|---|
| Vapour Pressure | 6.42E-13mmHg at 25°C |
|---|
| Index of Refraction | 1.633 |
|---|
| InChIKey | JPAUCQAJHLSMQW-XPORZQOISA-N |
|---|
| SMILES | Cc1ccc(OC2OC(C(=O)O)C(O)C(O)C2O)cc1 |
|---|
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|
| RIDADR | NONH for all modes of transport |
|---|
Articles3
More Articles
| Studies of catalysis by -glucuronidase. The effect of structure on the rate of hydrolysis of substituted phenyl- -d-glucopyranosiduronic acids. J. Biol. Chem. 247 , 2650-2656, (1972)
| |
| HPLC of phenolic glucuronides in isolated rabbit hepatocytes. Sawa, M., et al. Chromatographia 1988 , 247-250
| |
| Rates of hydrolysis of substituted phenyl β-D-gulcuronides by β-glucuronidase. Watabe, T., et al. Chem. Pharm. Bull. 18 , 414-415, (1970)
| |
Synonyms
| p-Tolyl-|A-D-glucuronide |
| 4-Methylphenol glucuronide |
| p-methylphenyl glucuronide |
| p-Cresol glucuronide |
| p-Tolyl-|A-D-glucuronic acid |
