CAS 69900-72-7|trimoprostil

Introduction：Basic information about CAS 69900-72-7|trimoprostil, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA

Common Name	trimoprostil
CAS Number	69900-72-7	Molecular Weight	378.54500
Density	1.043g/cm3	Boiling Point	528.2ºC at 760 mmHg
Molecular Formula	C₂₃H₃₈O₄	Melting Point	/
MSDS	/	Flash Point	287.3ºC

Names

Name	trimoprostil

Chemical & Physical Properties

Density	1.043g/cm3
Boiling Point	528.2ºC at 760 mmHg
Molecular Formula	C₂₃H₃₈O₄
Molecular Weight	378.54500
Flash Point	287.3ºC
Exact Mass	378.27700
PSA	74.60000
LogP	5.16240
Index of Refraction	1.527
InChIKey	OOAHNJDZICJECC-BHWPLRMJSA-N
SMILES	CCCCC(C)(C)C(O)C=CC1C(C)CC(=O)C1CC=CCCCC(=O)O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UK8010000

CHEMICAL NAME :: Prosta-5,13-dien-1-oic acid, 15-hydroxy-9-oxo-11,16,16-trimethyl-, (5Z,11-alpha,13E,15R)-

CAS REGISTRY NUMBER :: 69900-72-7

LAST UPDATED :: 199009

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C23-H38-O4

MOLECULAR WEIGHT :: 378.61

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 22 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: SHRIAI Shin'yaku to Rinsho. New Drugs and Clinics. (Shin'yaku to Rinsho Sha, 4-16-32 Fujimidai, Nerima-ku, Tokyo, 177, Japan) V.1- 1952- Volume(issue)/page/year: 35,2199,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 17 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: SHRIAI Shin'yaku to Rinsho. New Drugs and Clinics. (Shin'yaku to Rinsho Sha, 4-16-32 Fujimidai, Nerima-ku, Tokyo, 177, Japan) V.1- 1952- Volume(issue)/page/year: 35,2199,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 28 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: SHRIAI Shin'yaku to Rinsho. New Drugs and Clinics. (Shin'yaku to Rinsho Sha, 4-16-32 Fujimidai, Nerima-ku, Tokyo, 177, Japan) V.1- 1952- Volume(issue)/page/year: 35,2199,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 39 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea

REFERENCE :: SHRIAI Shin'yaku to Rinsho. New Drugs and Clinics. (Shin'yaku to Rinsho Sha, 4-16-32 Fujimidai, Nerima-ku, Tokyo, 177, Japan) V.1- 1952- Volume(issue)/page/year: 35,2199,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 62 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea

REFERENCE :: SHRIAI Shin'yaku to Rinsho. New Drugs and Clinics. (Shin'yaku to Rinsho Sha, 4-16-32 Fujimidai, Nerima-ku, Tokyo, 177, Japan) V.1- 1952- Volume(issue)/page/year: 35,2199,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 65 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea

REFERENCE :: SHRIAI Shin'yaku to Rinsho. New Drugs and Clinics. (Shin'yaku to Rinsho Sha, 4-16-32 Fujimidai, Nerima-ku, Tokyo, 177, Japan) V.1- 1952- Volume(issue)/page/year: 35,2199,1986

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