Introduction：Basic information about CAS 374750-30-8|2'-C-Methylguanosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2'-C-Methylguanosine |
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| CAS Number | 374750-30-8 | Molecular Weight | 297.27 |
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| Density | 2.0±0.1 g/cm3 | Boiling Point | 733.1±70.0 °C at 760 mmHg |
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| Molecular Formula | C11H15N5O5 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | 397.2±35.7 °C |
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Names
| Name | 2-amino-9-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-3H-purin-6-one |
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| Synonym | More Synonyms |
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2'-C-Methylguanosine BiologicalActivity
| Description | 2'-C-Methylguanosine (2'-C-beta-Methylguanosine) is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others |
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| References | [1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51. |
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Chemical & Physical Properties
| Density | 2.0±0.1 g/cm3 |
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| Boiling Point | 733.1±70.0 °C at 760 mmHg |
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| Molecular Formula | C11H15N5O5 |
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| Molecular Weight | 297.27 |
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| Flash Point | 397.2±35.7 °C |
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| Exact Mass | 297.107330 |
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| PSA | 159.51000 |
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| LogP | 0.34 |
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| Appearance of Characters | white to beige |
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| Vapour Pressure | 0.0±2.5 mmHg at 25°C |
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| Index of Refraction | 1.860 |
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| Storage condition | ?20°C |
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| Water Solubility | H2O: soluble5mg/mL, clear (warmed) |
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Safety Information
| RIDADR | NONH for all modes of transport |
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Synonyms
| 2`-C-Beta-Methyl Guanosine |
| 2'-METHYLGUANOSINE |
| 2'-C-Methylguanosine |
| Guanosine, 2'-C-methyl- |
| 2-amino-9-(2-C-methyl-β-D-ribofuranosyl)-9H-purin-6-ol |
| 9H-purin-6-ol, 2-amino-9-(2-C-methyl-β-D-ribofuranosyl)- |
