CAS 485-91-6|Allocryptopine

Introduction：Basic information about CAS 485-91-6|Allocryptopine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Allocryptopine BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Allocryptopine
CAS Number	485-91-6	Molecular Weight	369.411
Density	1.2±0.1 g/cm3	Boiling Point	552.7±50.0 °C at 760 mmHg
Molecular Formula	C₂₁H₂₃NO₅	Melting Point	/
MSDS	/	Flash Point	288.1±30.1 °C

Names

Name	allocryptopine
Synonym	More Synonyms

Allocryptopine BiologicalActivity

Description	Allocryptopine, a derivative of tetrahydropalmatine, is extracted from Corydalis decumbens (Thunb.) Pers. Papaveraceae. Allocryptopine has antiarrhythmic effects and potently blocks human ether-a-go-go related gene (hERG) current[1][2].
Related Catalog	Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Membrane Transporter/Ion Channel >>Potassium Channel
References	[1]. Xu B, et al. Effect of α-Allocryptopine on Delayed Afterdepolarizations and Triggered Activities in Mice Cardiomyocytes Treated with Isoproterenol. Evid Based Complement Alternat Med. 2015;2015:634172. [2]. Lin K, et al. Allocryptopine and benzyltetrahydropalmatine block hERG potassium channels expressed in HEK293 cells. Acta Pharmacol Sin. 2013 Jun;34(6):847-58.

Description

Allocryptopine, a derivative of tetrahydropalmatine, is extracted from Corydalis decumbens (Thunb.) Pers. Papaveraceae. Allocryptopine has antiarrhythmic effects and potently blocks human ether-a-go-go related gene (hERG) current[1][2].

Related Catalog

Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Membrane Transporter/Ion Channel >>Potassium Channel

References

[1]. Xu B, et al. Effect of α-Allocryptopine on Delayed Afterdepolarizations and Triggered Activities in Mice Cardiomyocytes Treated with Isoproterenol. Evid Based Complement Alternat Med. 2015;2015:634172.

[2]. Lin K, et al. Allocryptopine and benzyltetrahydropalmatine block hERG potassium channels expressed in HEK293 cells. Acta Pharmacol Sin. 2013 Jun;34(6):847-58.

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	552.7±50.0 °C at 760 mmHg
Molecular Formula	C₂₁H₂₃NO₅
Molecular Weight	369.411
Flash Point	288.1±30.1 °C
Exact Mass	369.157623
PSA	57.23000
LogP	3.64
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.574
Storage condition	2-8C

Synonyms

allo-Cryptopine

Allocryptopine

β-Homochelidonine

Benzo[c][1,3]benzodioxolo[5,6-g]azecin-14(6H)-one, 5,7,8,15-tetrahydro-3,4-dimethoxy-6-methyl-

[1,3]Benzodioxolo[5,6-e][2]benzazecin-14(6H)-one, 5,7,8,15-tetrahydro-3,4-dimethoxy-6-methyl-

5,7,8,15-Tetrahydro-3,4-dimethoxy-6-methylbenzo[e][1,3]dioxolo[4,5-k][3]benzazecin-14(6H)-one

5,7,8,15-Tetrahydro-3,4-dimethoxy-6-methylbenzo(e)(1,3)dioxolo(4,5-k)(3)benzazecin-14(6H)-one

Thalictrimine

Fagarine I

a-allo-Cryptopine

Benzo(e)(1,3)dioxolo(4,5-k)(3)benzazecin-14(6H)-one, 5,7,8,15-tetrahydro-3,4-dimethoxy-6-methyl-

3,4-Dimethoxy-6-methyl-5,7,8,15-tetrahydrobenzo[c][1,3]benzodioxolo[5,6-g]azecin-14(6H)-one

α-Fagarine

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