Introduction：Basic information about CAS 90614-49-6|Diprotin B, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Diprotin B |
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| CAS Number | 90614-49-6 | Molecular Weight | 327.41900 |
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| Density | 1.157 g/cm3 | Boiling Point | 575.9ºC at 760 mmHg |
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| Molecular Formula | C16H29N3O4 | Melting Point | / |
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| MSDS | / | Flash Point | 302.1ºC |
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Names
| Name | 2-[[1-(2-amino-3-methylbutanoyl)pyrrolidine-2-carbonyl]amino]-4-methylpentanoic acid |
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| Synonym | More Synonyms |
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Diprotin B BiologicalActivity
| Description | Diprotin B is a dipeptidyl aminopeptidase IV (DPP IV) inhibitor. The apparent competitive inhibition of DPP-IV by the diprotins is a kinetic artifact, derived from the substrate-like nature of tripeptides containing a penultimate proline residue[1][2]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Metabolic Enzyme/Protease >>Dipeptidyl Peptidase |
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Chemical & Physical Properties
| Density | 1.157 g/cm3 |
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| Boiling Point | 575.9ºC at 760 mmHg |
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| Molecular Formula | C16H29N3O4 |
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| Molecular Weight | 327.41900 |
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| Flash Point | 302.1ºC |
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| Exact Mass | 327.21600 |
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| PSA | 112.73000 |
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| LogP | 1.60530 |
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| Index of Refraction | 1.519 |
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| InChIKey | NHXZRXLFOBFMDM-AVGNSLFASA-N |
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| SMILES | CC(C)CC(NC(=O)C1CCCN1C(=O)C(N)C(C)C)C(=O)O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- OH3350000
- CHEMICAL NAME :
- L-Leucine, N-(1-L-valyl-L-prolyl)-
- CAS REGISTRY NUMBER :
- 90614-49-6
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C16-H29-N3-O4
- MOLECULAR WEIGHT :
- 327.48
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 37,422,1984
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Safety Information
Synonyms
| L-valyl-L-prolyl-L-leucine |
| VAL-PRO-LEU |
| Diprotin B |
